数据驱动的公共卫生安全  

Data-driven public health security

作　　者：李翠萍 吴林寰[2,5] 舒畅 鲍一明 马俊才[2,5] 宋述慧 Cuiping Li;Linhuan Wu;Chang Shu;Yiming Bao;Juncai Ma;Shuhui Song(National Genomics Data Center,Beijing Institute of Genomics,Chinese Academy of Sciences and China National Center for Bioinformation,Beijing 100101,China;National Microbiology Data Center,Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101,China;University of Chinese Academy of Sciences,Beijing 100049,China;CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences and China National Center for Bioinformation,Beijing 100101,China;Microbial Resources and Big Data Center,Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101,China;State Key Laboratory of Microbial Resources,Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101,China)

机构地区：[1]中国科学院北京基因组研究所(国家生物信息中心),国家基因组科学数据中心,北京100101 [2]中国科学院微生物研究所,国家微生物科学数据中心,北京100101 [3]中国科学院大学,北京100049 [4]中国科学院北京基因组研究所(国家生物信息中心),基因组科学与信息重点实验室,北京100101 [5]中国科学院微生物研究所,微生物资源与大数据中心,北京100101 [6]中国科学院微生物研究所,微生物资源前期开发国家重点实验室,北京100101

出　　处：《科学通报》2024年第9期1156-1163,共8页Chinese Science Bulletin

基　　金：2022年度“一带一路”国际科学组织联盟联合研究合作专项(ANSO-CR-KP-2022-09);国家自然科学基金(32270718);国家重点研发计划(2021YFF0703703,2023YFC3041500)资助。

摘　　要：在现代社会中,数据已成为重要的生产要素和国家基础性战略资源,是维护国家生物安全与社会稳定的利器[1].正确处理和利用数据,有助于我们及时、快速、有效地发现和解决问题,进一步维护社会的和谐稳定发展.在公共卫生安全领域,公共卫生安全事件成为21世纪人类生存面临的非传统安全威胁之一,特别是新发再发传染病对全球公共卫生和社会经济安全构成严重威胁[2,3].Public health security incidents have emerged as one of the most pressing threats to human survival in the 21st century.This is particularly evident with the resurgence and re-emergence of infectious diseases,which pose a grave risk to global public health and socio-economic stability.In light of these challenges,the rapid development of big data analysis technology has paved the way for data-driven public health security,a crucial tool in our arsenal for infectious disease prevention,control,and informed decision-making.Data-driven public health security revolves around the collection,analysis,and utilization of extensive big data resources to prevent and control epidemics,which can significantly enhance our ability to safeguard public health.Among the various categories of public health security big data,genetic data stands out as a pivotal component.It provides valuable insights into microbial pathogen evolution and aids in the judgment of epidemic development from a molecular genetic evolutionary perspective.Research in this field strives to offer a scientific foundation for managing public health security by comprehensively analyzing large-scale genetic data,ultimately empowering us to respond more effectively to diverse public health challenges.Effective compliance management,intelligent analysis,and scientific application of pathogen genetic data are vital for constructing a robust framework for public health security.Firstly,in the context of current global outbreaks,pathogen genetic data has become a cornerstone for epidemic prevention and control.The urgent need to manage these data in compliance with standards is paramount.Secondly,intelligent analysis technologies play a pivotal role in extracting hidden information from pathogen genetic-related data,providing precise guidance for infectious disease prevention and control.Through the integration and analysis of pathogen genetic data,we can track pathogen evolution,predict new variants and transmission paths,issue timely warnings about transmission ris

关 键 词：公共卫生安全 数据驱动 非传统安全威胁 全球公共卫生 和谐稳定发展 传染病 21世纪 基础性 

分 类 号：R-05[医药卫生]