地西泮在模拟养殖环境中的含量变化及累积特征  

Variation and accumulation characteristics of diazepam in simulated culture environment

作　　者：黄丽[1,2] 高磊 吴松[1,2] 郝其睿 李晨辉[1,2] 汤施展 白淑艳[1,2] 陈中祥 杜宁宁 覃东立[1,2,3] 王鹏 HUANG Li;GAO Lei;WU Song;HAO Qirui;LI Chenhui;TANG Shizhan;BAI Shuyan;CHEN Zhongxiang;DU Ningning;QIN Dongli;WANG Peng(Heilongjiang River Fisheries Research Institute,Chinese Academy of Fishery Sciences,Harbin 150070,China;Heilongjiang River Basin Fishery Ecological Environment Monitoring Center,Ministry of Agriculture and Rural Affairs,Harbin 150070,China;Key Laboratory of Control of Quality and Safety for Aquatic Products,Ministry of Agriculture and Rural Affairs,Beijing 100141,China)

机构地区：[1]中国水产科学研究院黑龙江水产研究所,黑龙江哈尔滨150070 [2]农业农村部黑龙江流域渔业生态环境监测中心,黑龙江哈尔滨150070 [3]农业农村部水产品质量安全控制重点实验室,北京100141

出　　处：《南方水产科学》2024年第2期38-47,共10页South China Fisheries Science

基　　金：中央级公益性科研院所基本科研业务费专项资金资助(HSY202112Q);国家重点研发计划项目(2020YFD0900301);中央财政经费政府购买服务项目(ZF2022512400,ZF2023660007);中国水产科学研究院中央级公益性科研院所基本科研业务费专项资金资助(2023TD60)。

摘　　要：为探究地西泮(Diazepam,DZP)在模拟养殖环境中的降解特点及累积特征,设置2个浓度胁迫组(A、C组),并在2个浓度下添加蜈蚣草(Pteris vittata)作对照组(B、D组),共4个试验组;分析水体、底泥和蜈蚣草中DZP浓度随时间的变化特点,探讨蜈蚣草和底泥对水体中DZP的累积特征。结果表明,给药后4组水体中DZP的初始质量浓度分别为A:(0.118±0.002)μg·L^(-1)、B:(0.117±0.004)μg·L^(-1)、C:(1.141±0.078)μg·L^(-1)和D:(1.142±0.039)μg·L^(-1),给药后第768小时水体中DZP质量浓度下降了29.71%~40.17%;DZP降解半衰期介于65.29~139.11 d。4组底泥中DZP质量分数随时间变化逐渐上升,给药768 h后4组底泥中DZP质量分数分别达到初始质量分数的17.99倍(1.384μg·kg^(-1))、14.81倍(0.918μg·kg^(-1))、4.77倍(7.848μg·kg^(-1))和5.30倍(7.763μg·kg^(-1)),富集系数介于9.79~18.80;B、D组蜈蚣草中DZP浓度峰值出现在给药后第216小时。蜈蚣草和底泥对水体中的DZP具有一定的吸附和富集作用,可明显缩短高浓度DZP在水中降解的半衰期,在低浓度DZP水体中添加蜈蚣草可抑制底泥对DZP的富集。In order to explore the degradation and accumulation characteristics of diazepam(DZP)in simulated culture environment,we set up four experimental groups including two different concentration stress groups(Group A and Group C)and two control groups(Group B and Group D)with addition of Pteris vittata to analyze the changes of DZP content in water,sediment and P.vittata with time,and to investigate the accumulation characteristics of DZP in water by P.vittata and sediment.The results show that the initial DZP mass concentrations in Group A,Group B,Group C and Group D were(0.118±0.002)μg·L^(-1),(0.117±0.004)μg·L^(-1),(1.141±0.078)μg·L^(-1) and(1.142±0.039)μg·L^(-1),respectively.The DZP concentration had decreased by 29.71%–40.17%after 768 h,and the degradation half-life period of DZP ranged from 65.29 d to 139.11 d.The DZP concentration in the sediment in the four groups increased gradually with time,reaching 17.99 times(1.384μg·kg^(-1),dry mass),14.81 times(0.918μg·kg^(-1),dry mass),4.77 times(7.848μg·kg^(-1),dry mass)and 5.30 times(7.763μg·kg^(-1),dry mass)of the initial concentration after 768 h of administration,respectively.The enrichment coefficients were 9.79–18.80.The peak concentration of DZP in Group B and Group D appeared after 216 h after administration.The adsorption and enrichment of DZP in water by P.vittata and the sediment can obviously shorten the degradation half-life period of high concentration DZP in water,and addition of P.vittata to low concentration DZP can inhibit the enrichment of DZP in sediment.

关 键 词：地西泮 模拟养殖环境 累计特征 半衰期 富集系数 

分 类 号：X131.2[环境科学与工程—环境科学] X52