探究高分辨率CT征象对GGN患者良恶性的临床诊断价值  

Clinical diagnostic value of high resolution CT signs for benignity or malignancy of GGN patients

作　　者：王丹雯 周建良[1] WANG Dan-wen;ZHOU Jian-liang(Department of Radiology,Wuzhong People's Hospital,Suzhou 215000,China)

机构地区：[1]苏州市吴中人民医院放射科,215000

出　　处：《中国现代药物应用》2024年第7期54-57,共4页Chinese Journal of Modern Drug Application

摘　　要：目的探究高分辨率CT征象对肺部磨玻璃结节(GGN)患者良恶性的临床诊断价值。方法82例GGN患者,根据肿瘤良恶性分为良性组(8例)和恶性组(74例)。所有患者均行高分辨率CT检查。比较两组高分辨率CT影像学特征(病灶大小、病灶形状、分叶征、毛刺征、界面、囊状透光影、空泡征、支气管征、血管集束征、密度、胸膜凹陷征),采用多因素Logistic回归分析恶性GGN患者的影像学危险因素,同时分析影像学检测对恶性GGN的诊断价值。结果两组病灶大小、病灶形状、空泡征、支气管征、血管集束征、胸膜凹陷征比较,无明显差异(P>0.05)。恶性组患者有分叶征55例、有毛刺征56例、有囊状透光影54例、界面清楚光整45例、界面清楚毛躁20例、界面模糊9例、密度为密度均匀的纯磨玻璃结节(pGGN)20例,良性组分别为1、2、1、1、1、6、6例,比较差异较大(P<0.05)。Logistic回归模型显示分叶征、毛刺征、囊状透光影、界面和密度是恶性GGN的影响因素(P<0.05)。高分辨率CT检测对恶性GGN的诊断价值最高的为分叶征,最低的为界面。结论对于GGN患者应用高分辨率CT检查,判别其良恶性效果较好,且分叶征诊断价值最高,可为临床诊断鉴别提供参考。Objective To explore the clinical diagnostic value of high resolution CT signs for benignity or malignancy of pulmonary ground-glass nodules(GGN)patients.Methods 82 patients with GGN were divided into benign group(8 patients)and malignant group(74 patients)according to benignity or malignancy of tumors.All patients underwent high-resolution CT.The high-resolution CT features(lesion size,lesion shape,lobular sign,burr sign,interface,cystic translucent shadow,vacuole sign,bronchus sign,vessel convergence,density,pleural indentation)of the two groups were compared.Multivariate Logistic regression was used to analyze the imaging risk factors of patients with malignant GGN,and the diagnostic value of imaging detection for malignant GGN was analyzed.Results There were no significant differences in lesion size,lesion shape,vacuole sign,bronchial sign,vessel convergence and pleural indentation between the two groups(P>0.05).In the malignant group,55 cases had lobed signs,56 cases had burr signs,54 cases had cystic transparent light,45 cases had clear smooth interface,20 cases had clear frizz interface,9 cases had fuzzy interface,and 20 cases had pure ground-glass nodules(PGGN)density,which was significantly different from 1,2,1,1,1,6,6 cases in the benign group(P<0.05).Logistic regression model showed that lobed sign,burr sign,cystic translucent shadow,interface and density were the influencing factors of malignant GGN(P<0.05).The highest diagnostic value of high-resolution CT for malignant GGN was the lobular sign,and the lowest was the interface.Conclusion The application of high-resolution CT for patients with GGN has a better effect in discriminating its benignity or malignancy,and the highest diagnostic value of lobular sign can provide a reference for clinical diagnosis and differentiation.

关 键 词：高分辨率CT 征象 肺部磨玻璃结节 良恶性 诊断 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]