^(125)I粒子近距离照射在口腔颌面部恶性肿瘤治疗中的临床应用进展  

Progress in clinical application of ^(125)I seeds brachytherapy in the treatment of oral and maxillofacial malignant tumors

作　　者：魏婷 倪前伟[2] 杨自更[3] 黄孝泳 孙海涛[4] 孙睿哲 马超 蔡冰冰[3] 高瞻[2] Wei Ting;Ni Qianwei;Yang Zigeng;Huang Xiaoyong;Sun Haitao;Sun Ruizhe;Ma Chao;Cai Bingbing;Gao Zhan(Graduate School of Xinjiang Medical University,Urumqi 830054,China;Department of Oral and Maxillofacial Surgery,General Hospital of Xinjiang Military Command,Urumqi 830000,China;Department of Nuclear Medicine,General Hospital of Xinjiang Military Command,Urumqi 830000,China;Department of Radiation Oncology,Peking University Third Hospital,Beijing 100191,China;Department of Medical Imaging,General Hospital of Xinjiang Military Command,Urumqi 830000,China)

机构地区：[1]新疆医科大学研究生院,乌鲁木齐830054 [2]新疆军区总医院颌面外科,乌鲁木齐830000 [3]新疆军区总医院核医学科,乌鲁木齐830000 [4]北京大学第三医院肿瘤放疗科,北京100191 [5]新疆军区总医院医学影像科,乌鲁木齐830000

出　　处：《中华核医学与分子影像杂志》2024年第4期253-256,共4页Chinese Journal of Nuclear Medicine and Molecular Imaging

基　　金：中华口腔医学会西部口腔医学临床科研基金(CSA-W2020-06)。

摘　　要：口腔颌面部恶性肿瘤威胁患者生命健康,严重影响患者的吞咽、语言功能和面容。其治疗方法中,^(125)I粒子近距离照射治疗技术因手术创伤小,靶区组织剂量大分布均匀,对周边正常组织损伤小,可以减少医护人员辐射暴露等优点,受到广泛关注。利用^(125)I粒子对口腔颌面部肿瘤进行持续、低剂量的近距离照射治疗,可以有效减小肿瘤体积,延长患者的生存期,治疗效果显著。该文针对^(125)I粒子近距离照射在口腔颌面部恶性肿瘤的临床应用展开综述。Oral and maxillofacial malignant tumors threaten the life and health of patients,and seriously affect their swallowing,language function and face.^(125)I seeds brachytherapy for oral and maxillofacial malignant tumors has been widely concerned and studied because of its advantages such as less surgical trauma,large and uniform dose distribution in the target tissue,little damage to the surrounding normal tissue,and reducing radiation exposure of medical staff.Low-dose brachytherapy with ^(125)I seeds can effectively reduce the tumor volume and prolong the survival time of patients.This article reviews the clinical application of ^(125)I seeds brachytherapy in oral and maxillofacial malignant tumors.

关 键 词：口腔肿瘤 近距离放射疗法 碘放射性同位素 发展趋势 

分 类 号：R739.8[医药卫生—肿瘤]