蜜蜂气味结合蛋白与外源性化合物互作机制研究进展  

Research progress on the interaction mechanism of honey bee odorant-binding proteins with exogenous compounds

作　　者：陈沛彤 鄢茹 朱国念[1] 陈梦丽 郭逸蓉[1] CHEN Peitong;YAN Ru;ZHU Guonian;CHEN Mengli;GUO Yirong(Institute of Pesticide And Environmental Toxicology,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou 310058,China;College of Life Sciences,Zhejiang University,Hangzhou 310058,China;College of Advanced Agricultural Sciences,Zhejiang Agriculture and Forestry University,Hangzhou 311300,China)

机构地区：[1]浙江大学农业与生物技术学院农药与环境毒理研究所,杭州310058 [2]浙江大学生命科学学院,杭州310058 [3]浙江农林大学现代农学院,杭州311300

出　　处：《农药学学报》2024年第2期257-265,共9页Chinese Journal of Pesticide Science

基　　金：浙江省自然科学基金项目(LQ24C040001).

摘　　要：嗅觉是蜜蜂赖以生存和繁殖的主要感官方式,可为蜜蜂外出觅食、躲避天敌、交配等行为提供重要信息,而气味结合蛋白(odorant-binding proteins,OBPs)在其嗅觉感知中发挥着关键作用。探究外界环境中各种化学物质与蜜蜂OBPs之间的相互作用,对于揭示蜜蜂OBPs对不同外源性化合物的结合特性和结合机制具有重要意义。外源性化合物主要包括化学信息物质(信息素和蜜源开花植物挥发物)以及杀虫剂等农用化学品。一方面,化学信息物质与蜜蜂OBPs结合,在维持蜂群稳定、繁殖、觅食、授粉等生理功能中发挥着重要作用;另一方面,杀虫剂与蜜蜂OBPs结合则可能危害蜜蜂嗅觉系统,影响或干扰蜜蜂对环境气味分子的识别。本文综述了蜜蜂OBPs的种类、功能及其与外源性化合物互作机制的研究进展,以期为深入探究蜜蜂OBPs的生理功能、保护蜜蜂免受杀虫剂等化学物质的危害提供参考。Olfactory is the main sense for the survival and reproduction of honey bees,providing important information for honey bees to forage,mate,escape from natural enemies,and other behaviors.Odorant-binding proteins(OBPs)play a crucial role in bees'olfactory perception.Therefore,exploring the interaction between honey bee OBPs and various chemicals in the environment is of significant importance for elucidating the binding characteristics and mechanisms of honey bee OBPs towards different exogenous compounds,including semiochemicals,pheromones,plant volatiles,and insecticides.On one hand,the binding of semiochemicals with bee OBPs plays a crucial role in maintaining bee colony stability,reproduction,foraging,pollination,and other physiological functions.On the other hand,the binding of insecticides with OBPs may pose a threat to the bee's olfactory system,affecting the bee’s ability to recognize environmental odor molecules.In this review,we summarize the research progress on the types,and functions of bee OBPs,as well as the research progress on their interaction mechanisms with exogenous compounds.The aim is to offer a reference basis for further exploration of the physiological functions of bee OBPs and for protecting bees from the harm of pesticides and other chemicals.

关 键 词：蜜蜂 气味结合蛋白 嗅觉感受器 互作机制 杀虫剂 昆虫信息素 植物挥发性物质 

分 类 号：S891[农业科学—特种经济动物饲养] S481.1[农业科学—畜牧兽医]