积极心理干预对难治性急性白血病患者化疗过程中癌症复发恐惧感和生活质量的改善作用  

Effect of positive psychology intervention in reducing the fear of cancer recurrence and improving the quality of life in patients with refractory acute leukemia during chemotherapy

作　　者：伍春花 赵慧函 徐夏 黄丽明 李焱[1] 谢芳梅[1] 庹印芬 周雪梅[2] WU Chunhua;ZHAO Huihan;XU Xia(Department of Hematology,the First Affiliated Hospital of Guangxi Medical University,Guangxi,Nanning 530000,China)

机构地区：[1]广西医科大学第一附属医院血液内科,南宁市530000 [2]广西医科大学第一附属医院干细胞移植中心,南宁市530000

出　　处：《河北医药》2024年第7期1041-1044,共4页Hebei Medical Journal

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(编号:Z20190588)。

摘　　要：目的分析化疗中难治性急性白血病(refractory acute leukemia thurberg,RALT)患者接受积极心理干预的效果。方法以数字编号信封法将65例RALT患者分组,A组(31例,常规干预)、B组(34例,积极心理干预),比较2组干预效果。结果干预后B组FOP-Q-SF评分[焦虑疾病可能复发(1.26±0.37)分、定期复查前紧张(1.23±0.31)分、恐惧用药损伤健康(1.24±0.35)分、焦虑疾病影响工作(1.26±0.34)分、总分(15.24±3.73)分]、SF-36评分[躯体功能(15.63±2.26)分、社会功能(7.72±1.23)分、生理功能(23.35±3.21)分、心理功能(20.48±2.26)分、精神健康(23.46±3.27)分]、HAMD评分[抑郁情绪(0.86±0.23)分、强迫症状(0.84±0.25)分、睡眠障碍(0.87±0.24)分、自卑感(0.83±0.22)分、偏执症状(0.85±0.27)分]、HHI评分、并发症率发生率优于A组(P<0.05)。结论化疗中RALT患者接受积极心理干预,能使患者对癌症复发的恐惧感、不良心理状态有效改善,提高其生活质量和希望水平,同时能在一定程度上预防并发症。Objective To analyze the effects of positive psychology intervention in patients with refractory acute leukemia(RAL)during chemotherapy.Methods Totally 65 patients with RAL treated in our hospital were divided into group A(31 cases,routine intervention)and group B(34 cases,positive psychology intervention)by envelope method with digital serial number.The intervention effect of the two groups was compared.Results After the intervention,the Fear of Progression Questionnaire-Short Form(FoP-Q-SF)scores of group B(possible recurrence of anxiety disease:[1.26±0.37]points,stress before regular review:[1.23±0.31]points,fear of drug damage to health:[1.24±0.35]points,anxiety disease affecting work:[1.26±0.34]points,total score:[15.24±3.73]points),the 36-Item Short Form Health Survey(SF-36)scores(physical function:[15.63±2.26]points,social function:[7.72±1.23]points,physiological function:[23.35±3.21]points,psychological function:[20.48±2.26]points,mental health:[23.46±3.27]points),Hamilton Depression Rating Scale(HAMD)scores(depression:[0.86±0.23]points,obsessive-compulsive symptoms:[0.84±0.25]points,dyssomnia:[0.87±0.24]points,inferiority:[0.83±0.22]points,paranoid symptoms:0.85±0.27 points),the Herth Hope Index(HHI)score and complication rate were significantly better than those in group A(P<0.05).Conclusion Positive psychology intervention can effectively improve the fear of cancer recurrence and negative psychological state of patients with RAL,improve the quality of life and level of hope,and prevent complications to a certain extent.

关 键 词：难治性急性白血病 化疗 积极心理干预 癌症复发恐惧感 生活质量 

分 类 号：R733.71[医药卫生—肿瘤]