音乐疗法对抑郁情绪的影响  

Effect of music therapy on depression:A randomized controlled trial

作　　者：程月红 王雨静 徐琳[1] CHENG Yuehong;WANG Yujing;XU Lin(Department of Mental Health,the First Hospital of Hebei Medical University,Mental Health Center of Hebei Medical University,Hebei,Shijiazhuang 050031,China)

机构地区：[1]河北医科大学第一医院精神卫生科河北医科大学精神卫生中心,石家庄市050031

出　　处：《河北医药》2024年第7期1091-1094,共4页Hebei Medical Journal

基　　金：河北省卫健委医学科学研究课题(编号:20190467)。

摘　　要：目的探讨音乐疗法对抑郁症患者情绪的影响。方法选取2018年9月至2019年9月在河北医科大学第一医院精神卫生中心住院的102例抑郁症患者作为研究对象,采用随机数字表法随机分为对照组和研究组,每组51例。研究组采用音乐疗法联合抗抑郁(SSRIs)药物治疗,对照组单独SSRIs药物治疗,采用HAMD量表对患者抑郁情绪的严重程度进行评估。获取患者基本人口学资料:性别、年龄、性格、合并症、发作次数、职业、文化程度、婚姻状况、家庭经济状况等。在基线、治疗第1周、治疗第2周、治疗第4周采用HAMD量表评估患者抑郁情绪的严重程度。结果不同时间点HAMD差异有统计学意义(F时间=1033.961,P时间<0.001),组别与时间点间存在交互作用(F=4.405,P=0.014)。进一步分析单独的效应,第3和第4时间点研究组的HAMD的减分率均高于对照组(P<0.05)。不同特征患者HAMD比较,结果显示治疗后研究组HAMD评分明显低于对照组,男性HAMD高于女性,年龄36~59、≥60岁HAMD高于18~35岁患者,内向性格患者HAMD高于中性性格,在职人员高于非在职人员,差异均有统计学意义(P<0.05)。组别和入组HAMD为治疗后HAMD的独立影响因素,研究组HAMD低于对照组(P=0.001),入组HAMD越高,治疗后HAMD越高(P<0.001),其余因素对治疗后HAMD均无影响(P>0.05)。结论音乐疗法在辅助改善抑郁症患者的抑郁情绪有积极影响,联合药物治疗能够快速缓解患者的抑郁情绪。Objective To explore the effect of music therapy on the mood of patients with depression.Methods A total of 102 patients with depression hospitalized in the psychiatric department of The first hospital of Hebei Medical University from September 2018 to September 2019 were recruited.They were randomly divided into control group(n=51)and study group(n=51).Patients in the study group received music therapy combined with drug intervention of selective?serotonin reuptake inhibitors(SSRIs),whereas patients in the control group only received the latter.The basic demographic data of the patient:gender,age,personality,complications,number of attacks,occupation,education level,marital status,family economic status were collected.Hamilton Depression Rating Scale(HAMD)was used to assess the severity of depression on day 0 and weeks 1,2,4 of treatment.Results There were statistically significant differences in HAMD score at different time points(F=1033.961,P<0.001),and there was an interaction between groups and time points(F=4.405,P=0.014).Further analysis of individual effects showed that HAMD scores at the third and fourth time points in the study group were significantly higher than those of the control group(P<0.05).In comparing the HAMD of patients with different characteristics,HAMD score of the study group was significantly lower than that of the control group,HAMD score of the male was significantly higher than that of the female,HAMD score of the patients aged 36-59 and≥60 was significantly higher than that of the patients aged 18-35,the HAMD score of the patients with introverted personality was significantly higher than that of the neutral personality,and the HAMD score of the on-the-job staff was significantly higher than that of the non-on-the-job staff,the differences were statistically significant(P<0.05).Group and enrolled HAMD were independent influencing factors of post-treatment HAMD.HAMD score in the study group was significantly lower than that of the control group(P=0.001).The higher the enrolled HAMD

关 键 词：音乐疗法 抑郁症 随机对照 初步观察 

分 类 号：R749.41[医药卫生—神经病学与精神病学]