玻璃体切除联合黄斑前膜剥除术及内界膜剥除术在特发性黄斑前膜患者中的治疗效果分析  

Efficacy of Vitrectomy Combined with Anterior Macular Membrane Stripping and Internal Boundary Membrane Stripping in Patients with Idiopathic Anterior Macular Membrane

作　　者：秦剑莺 顾育红[1] 周婷 QIN Jianying;GU Yuhong;ZHOU Ting(Department of Ophthalmology,Changshu First People's Hospital,Changshu,Jiangsu Province,215500 China)

机构地区：[1]常熟市第一人民医院眼科,江苏常熟215500

出　　处：《系统医学》2024年第4期31-34,共4页Systems Medicine

摘　　要：目的 探究玻璃体切除联合黄斑前膜剥除术及内界膜剥除在特发性黄斑视网膜前膜(简称“特发性黄斑前膜”)患者中的治疗效果。方法 选取2019年5月—2023年5月常熟市第一人民医院眼科收治的60例特发性黄斑前膜患者作为研究对象,按照随机数表法分为两组。对照组(n=30)实施玻璃体切除联合黄斑前膜剥除术,研究组(n=30)在对照组基础上联合内界膜剥除治疗,对比两组视力(Best-corrected Visual Acuity,BCVA)、黄斑中心凹视网膜厚度(Central Macular Thickness,CMT)、平均视物变形评分、并发症发生率。结果术后1个月,研究组的BCVA优于对照组,差异有统计学意义(P<0.05);研究组术后3个月CMT低于对照组,差异有统计学意义(P<0.05);两组患者术后1个月、3个月平均视物变形评分均低于术前,差异有统计学意义(P均<0.05),组间比较,差异无统计学意义(P均>0.05);研究组并发症总发生率与对照组比较,差异无统计学意义(P>0.05)。结论 玻璃体切除联合黄斑前膜剥除术和内界膜剥除术两种手术方式对特发性黄斑前膜患者治疗均具备良好的治疗效果,安全性较好,但在改善视网膜厚度方面,玻璃体切除联合黄斑前膜剥除及内界膜剥除术后更低,体现出一定优势,但临床还需更大样本量进一步研究,根据患者实际给予合理手术方式的选择。Objective To explore the therapeutic effect of vitrectomy combined with anterior macular membrane stripping and internal boundary membrane stripping in patients with idiopathic anterior macular membrane.Methods A total of 60 patients with idiopathic macular anterior membrane admitted to the Ophthalmology Department of the First People's Hospital of Changshu City from May 2019 to May 2023 were selected as the study objects and divided into two groups according to random number table method.The control group(n=30) underwent vitrectomy with anterior macular membrane stripping,and the study group(n=30) combined with internal boundary membrane stripping based on the treatment of the control group.The best corrected visual acuity(BCVA),central macular thickness(CMT),average M-charts score and complication rate were compared between the two groups.Results 1 month after surgery,BCVA of the study group was better than that of the control group,and the difference was statistically significant(P<0.05).CMT 3 months after operation in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The average M-charts score of two groups 1,3 months after surgery were lower than before surgery,the differences were statistically significant(both P<0.05),but there was no statistically significant difference between two groups(both P>0.05).There was no significant difference in the complication total rate between the study group and the control group(P>0.05).Conclusion Both vitrectomy combined with macular anterior membrane stripping and internal boundary membrane stripping have good therapeutic effects and good safety in the treatment of patients with idiopathic macular anterior membrane.However,vitrectomy combined with macular anterior membrane stripping and internal boundary membrane stripping are lower after surgery in terms of improving retinal thickness,reflecting certain advantages.However,further studies with larger sample size are needed in clinical practice,and reasonabl

关 键 词：玻璃体切除 黄斑前膜剥除术 内界膜剥除 特发性黄斑前膜 

分 类 号：R779[医药卫生—眼科]