低频脉冲治疗对老年晚期恶性肿瘤化疗后骨髓抑制的有效性探讨  

Exploration of the Effectiveness of Low-frequency Pulse Therapy on Myelosuppression after Chemotherapy for Advanced Malignant Tumors in Elderly People

作　　者：李海燕 陈湘燕 王娟 LI Haiyan;CHEN Xiangyan;WANG Juan(Department of Oncology,Taizhou Jiangyan Hospital of Traditional Chinese Medicine,Taizhou,Jiangsu Province,225500 China)

机构地区：[1]泰州市姜堰中医院肿瘤科,江苏泰州225500

出　　处：《系统医学》2024年第4期162-164,168,共4页Systems Medicine

摘　　要：目的 探究低频脉冲治疗对老年晚期恶性肿瘤化疗后骨髓抑制的有效性。方法 选取泰州市姜堰中医院肿瘤科于2020年1月—2022年12月收治的60例老年晚期恶性肿瘤化疗后骨髓抑制患者为研究对象,按照随机抽签法分为对照组(予以常规对症治疗)、观察组(在常规对症治疗基础上辅以低频脉冲治疗),各30例。对比两组骨髓抑制严重程度、健康状况、生活质量,所用工具为卡氏评分(Karnofsky Performance Score,KPS)、癌症患者生命质量测定量表(Functional Assessment of Cancer Therapy,FACT-G)。结果 治疗后,观察组骨髓抑制程度优于对照组,差异有统计学意义(Z=-2.023,P<0.05)。治疗后,观察组KPS评分为(89.21±5.11)分,FACT-G评分为(88.23±6.11)分,高于对照组的(77.71±4.33)分、(75.61±5.31)分,差异有统计学意义(t=9.404、8.539,P均<0.05)。结论 低频脉冲治疗的辅助价值更高,可有效减轻患者病情严重程度,提高机体健康水平,改善生活质量。Objective To explore the effectiveness of low-frequency pulse therapy on myelosuppression after chemotherapy for advanced malignant tumors in the elderly.Methods A total of 60 patients with myelosuppression after chemotherapy for advanced malignant tumors admitted to the Department of Oncology,Taizhou Jiangyan Hospital of Traditional Chinese Medicine from January 2020 to December 2022 were selected as the study objects,and they were divided into the control group(treated with conventional symptomatic therapy) and the observation group(supplemented with low-frequency pulse therapy on the basis of conventional symptomatic therapy) according to the method of random drawing,with 30 cases in each group.The severity of myelosuppression,health status,and quality of life were compared between the two groups,and the tools used were karnofsky performance score(KPS) and functional assessment of cancer therapy(FACT-G).Results After treatment,the degree of myelosuppression in the observation group was better than that in the control group,and the difference was statistically significant(Z=-2.023,P<0.05).In the observation group,KPS score was(89.21±5.11) points and FACT-G score was(88.23±6.11) points,which were higher than(77.71±4.33) points and(75.61±5.31) points of the control group,and the differences were statistically significant(t=9.404,8.539,both P<0.05).Conclusion Low-frequency pulse therapy has a higher auxiliary value,can effectively reduce the severity of the patient's condition,improve the health level of the organism and the quality of life.

关 键 词：老年 晚期恶性肿瘤化疗后骨髓抑制 低频脉冲治疗 经皮穴位电刺激 效果观察 

分 类 号：R735.7[医药卫生—肿瘤]