双相障碍患者新型冠状病毒感染后紧张症1例  

A case of catatonia after COVID-19 infection in a patient with bipolar disorder

作　　者：孙莞绮 汪崇泽 吕钦谕[1] Sun Wanqi;Wang Chongze;Lyu Qinyu(Shanghai Mental Health Center,Shanghai Jiaotong University School of Medicine,Shanghai 200030,China)

机构地区：[1]上海交通大学医学院附属精神卫生中心,上海200030

出　　处：《中华精神科杂志》2024年第4期234-238,共5页Chinese Journal of Psychiatry

基　　金：科技创新2030脑科学与类脑研究重大项目(2022ZD0208500)。

摘　　要：新型冠状病毒感染引起的精神症状在临床并不少见,除了常见的焦虑、抑郁和失眠之外,感染也导致新发精神病性症状或使原有精神症状加重。本文报告1例有双相障碍疾病史的患者,在新型冠状病毒感染后出现紧张症的临床表现。通过神经系统体检、脑影像检查和脑脊液检查,证实了患者存在神经系统损伤。经过劳拉西泮、糖皮质激素和小剂量抗精神病药治疗后,患者的紧张症明显缓解。临床医生应重视新型冠状病毒感染对神经系统造成的损伤,以期对新型冠状病毒感染后出现精神症状的患者进行全面分析、诊断和综合治疗。Psychiatric symptoms caused by COVID-19(SARS-CoV-2)infection are common in clinical practice.In addition to the anxiety,depression,and insomnia,which are often seen,COVID-19 infection also leads to new onset of psychotic symptoms or exacerbation of pre-existing psychiatric symptoms.This study reported a case of a patient with a history of bipolar disorder who presented with clinical manifestations of catatonia after COVID-19 infection.Neurological impairments in this patient were confirmed by neurological physical examination,brain imaging,and cerebrospinal fluid examination.After treatment with lorazepam,glucocorticoids,and low-dose antipsychotics,the patient′s catatonia was significantly relieved.Clinicians should pay attention to the neurological damage caused by COVID-19 infection to be providing comprehensive analysis,diagnosis,and integrated treatment for patients who develop psychiatric symptoms after COVID-19 infection.

关 键 词：紧张症 双相情感障碍 新型冠状病毒 

分 类 号：R74[医药卫生—神经病学与精神病学]