Recent Advances in Catalytic Carbonylation Reactions in Alternative Reaction Media  

作　　者：Csaba Árvai László T.Mika 

机构地区：[1]Department of Chemical and Environmental Process Engineering,Faculty of Chemical Technology and Biotechnology,Budapest University of Technology and Economics,Műegyetem rkp.3,H-1111 Budapest,Hungary

出　　处：《Chinese Journal of Chemistry》2024年第4期406-429,共24页中国化学（英文版）

基　　金：National Research,Development and Innovation Office-NKFIH under project number of FK 143197 and 2019-1.3.1-KK-2019-00004.TKP2021-EGA-02,implemented with the support provided by the Ministry for Innovation and Technology of Hungary from the National Research,Development and Innovation Fund,financed under the TKP2021 funding scheme.

摘　　要：Since the discovery of the hydroformylation(oxo-synthesis or Roelen reaction)and the Reppe-reaction,the transition metal-catalyzed carbonylation reactions,providing versatile,facile,and even atom-economic methods for the selective incorporation of C=O functionality to various skeletons,have gained tremendous importance in synthetic organic chemistry from laboratories to industrial applications.The carbonylation of carbon-carbon multiple bonds,aromatic halides,triflates,etc.,in the presence of various nucleophiles has led the way to produce aldehydes,carboxylic acids,esters,amides,etc.,in the fine chemical industry.However,these protocols usually proceed in conventional,fossil-based,and usually toxic reaction environments.Thus,several attempts have been directed to developing efficient carbonylation methods in alternative,less harmful,non-fossil-based and even in renewable reaction media.In this review,we overview the recent applications of alternative solvents such as water,biomass-based alcohols,γ-valerolactone(GVL),2-methyltetrahydrofuran(2-MeTHF),ionic liquids(ILs),deep eutectic solvents(DES),alkyl levulinates,limonene,α-pinene,and dimethyl carbonate as well as fluorous media to improve efficiency,safety and environmentally benign nature of carbonylation protocols.

关 键 词：CARBONYLATION CATALYSIS Solvents Green chemistry Carbon monoxide Transition metals Homogeneous catalysis PALLADIUM 

分 类 号：O62[理学—有机化学]