功能性电刺激联合核心肌群训练对脑卒中偏瘫患者下肢功能和血清Aβ与Tau的影响  

Effects of functional electrical stimulation combined with core muscle group training on lower limb function and Aβand Tau protein in stroke patients with hemiplegia

作　　者：邱锦芳 郭峰[1] 林军[1] QIU Jin-fang;GUO Feng;LIN Jun(Department of Cadre Health Care,Zhongshan Hospital,Xiamen University,Xiamen 361000,Fujian,China)

机构地区：[1]厦门大学附属中山医院干部保健科,福建厦门361000

出　　处：《川北医学院学报》2024年第4期524-527,共4页Journal of North Sichuan Medical College

基　　金：福建省厦门市医疗卫生指导性项目(3502Z20209040)。

摘　　要：目的:探讨在核心肌群训练基础上对脑卒中偏瘫患者予以功能性电刺激(FES)治疗对下肢功能恢复的影响。方法:按治疗方式不同,将96例脑卒中偏瘫患者分为对照组(n=48)与观察组(n=48),两组均进行常规治疗。对照组予以核心肌群训练;观察组予以FES治疗联合核心肌群训练,两组均治疗4周。于治疗前后比较两组下肢运动功能[简化Fugl-Meyer下肢运动功能量表(FMA-LE)]、平衡功能[Berg平衡量表(BBS)]、步行功能[功能性步行能力分级(FAC)、10 m步行时间测试(10MWT)、6 min步行距离测试(6MWT)]、日常生活能力[改良Barthel指数(MBI)]和神经功能[美国国立卫生研究院卒中量表(NHISS)]的评定,并进行血清β-淀粉样蛋白(Aβ)、Tau蛋白水平的测定。结果:治疗后,观察组患者FMA-LE评分和BBS评分高于对照组(P<0.05),6MWT和FAC分级高于对照组(P<0.05);10MWT低于对照组(P<0.05),MBI评分高于对照组(P<0.05);NHISS评分低于对照组(P<0.05)。治疗后,观察组血清Aβ、Tau水平低于对照组(P<0.05)。结论:FES联合核心肌群训练能够改善脑卒中偏瘫患者下肢运动功能、平衡功能和步行能力,降低血清Aβ、Tau水平,疗效显著。Objective:To investigate the effect of functional electrical stimulation(FES)on the recovery of lower limb function in stroke patients with hemiplegia on the basis of core muscle group training.Methods:According to the different treatment methods,96 stroke patients with hemiplegia were divided into control group(n=48)and observation group(n=48).Both groups were given routine treatment.In addition,the control group was given core muscle group training,and the observation group was given FES treatment combined with core muscle group training.Both groups were treated for 4 weeks.Before and after 4 weeks of treatment,the lower limb motor function[simplified Fugl-Meyer lower limb motor function scale(FMA-LE)],balance function[Berg balance scale(BBS)],walking function[functional walking ability classification(FAC),10 min walking time test(10MWT),6 min walking distance test(6MWT)],daily living ability[modified Barthel index(MBI)]and neurological function[National Institutes of Health Stroke Scale(NHISS)]were evaluated.Serumβ-amyloid protein(Aβ)and Tau protein were measured.Results:After treatment,the FMA-LE score and BBS score of the observation group were higher than those of the control group(P<0.05).The 6MWT and FAC grades of the observation group were higher than those of the control group(P<0.05),and the 10MWT was lower than the control group(P<0.05).The MBI score of the observation group was higher than that of the control group(P<0.05),and the NHISS score of the observation group was lower than that of the control group(P<0.05).After treatment,the levels of serum Aβand Tau protein in the observation group were lower than those of the control group(P<0.05).Conclusion:FES combined with core muscle group training can improve the lower limb motor function,balance function and walking ability of stroke patients with hemiplegia,and reduce the levels of serum Aβand Tau protein.

关 键 词：脑卒中 下肢运动功能 步行能力 核心肌群训练 功能性电刺激 

分 类 号：R743.3[医药卫生—神经病学与精神病学]