单孔加一孔腹腔镜手术与传统腹腔镜手术治疗乙状结肠癌的疗效与分析  

Effect and analysis of single plus one hole laparoscopic surgery and traditional laparoscopic surgery in the treatment of sigmoid carcinoma

作　　者：聂彬 赵铁军 于云宝 李欢 谢林峻 Nie Bin;Zhao Tiejun;Yu Yunbao;Li Huan;Xie Linjun(Department of General Surgery,Chengdu BOE Hospital,Chengdu Sichuan Province 610000,China)

机构地区：[1]成都京东方医院普外科,四川成都610000

出　　处：《中华普外科手术学杂志（电子版）》2024年第3期330-333,共4页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)

基　　金：成都市卫生和计划生育委员会项目(编号:2017106)。

摘　　要：目的探讨单孔加一孔腹腔镜手术(SILS+1)与传统腹腔镜手术治疗乙状结肠癌的疗效。方法回顾性分析2019年3月至2021年5月86例乙状结肠癌患者资料,根据术式不同分为两组。研究组(n=40,采用SILS+1术式)和对照组(n=46,采用传统5孔法腹腔镜术式)。用SPSS 19.0软件进行统计学分析。围手术期指标、术后标本病理的差异情况和手术前后炎性指标等计量资料用(x±s)表示,组间比较采用独立样本t检验。结果研究组患者总切口长度、首次下床时间、首次排便时间及术后住院时间均优于对照组(P<0.05);两组患者术后标本病理情况比较无差异(P>0.05);所有患者术后C反应蛋白和肿瘤坏死因子α均较术前升高,但对照组升高更为显著(P<0.05);术后一年,两组患者总生存率及复发率比较无差异(P>0.05)。结论单孔加一孔腹腔镜手术不仅可达到传统腹腔镜手术同样的根治效果,同时还可减轻机体的炎性反应,从而加快患者的康复速度,且不影响患者的预后,值得临床推广应用。Objective To investigate the efficacy of single aperture plus one aperture laparoscopic surgery(SILS+1)versus traditional laparoscopic surgery in the treatment of sigmoid carcinoma.Methods Data of 86 patients with sigmoid carcinoma from March 2019 to May 2021 were retrospectively analyzed and divided into two groups according to different operation methods.Study group(n=40,SILS+1 surgery)and control group(n=46,traditional 5-hole laparoscopic surgery).SPSS 19.0 software was used for statistical analysis.Measurement data such as perioperative indicators,pathological differences of postoperative specimens and inflammatory indicators before and after surgery were expressed with(x±s).Independent sample t test was used for comparison between groups.Results The total incision length,first time of getting out of bed,first defecation time and postoperative hospitalization time in the study group were better than those in the control group(P<0.05).There was no difference in the pathological status of postoperative specimens between the two groups(P>0.05).C-reactive protein and tumor necrosis factorαwere increased in all patients after operation,but the increases were more significant in control group(P<0.05).One year after surgery,there was no difference in overall survival rate and recurrence rate between the two groups(P>0.05).Conclusion Single-hole plus one-hole laparoscopic surgery can not only achieve the same radical curative effect as traditional laparoscopic surgery,but also reduce the inflammatory response of the body,thus speeding up the recovery of patients,and does not affect the prognosis of patients,which is worthy of clinical promotion and application.

关 键 词：乙状结肠癌 乙状结肠癌根治术 腹腔镜 单孔加一孔 炎性指标 预后 

分 类 号：R735.35[医药卫生—肿瘤]