肺部结节性病变临床与病理表现分析  

Clinical and Pathological Analysis of Pulmonary Nodular Lesions

作　　者：刘晓莉[1] 张小丹[1] Liu Xiaoli;Zhang Xiaodan(Department of Pathology,Dongtai Hospital of Traditional Chinese Medicine,Yancheng 224200,Jiangsu Province,China)

机构地区：[1]东台市中医院病理科,江苏盐城224200

出　　处：《中外医药研究》2024年第6期12-14,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析肺部结节性病变临床与病理表现。方法:选取2016年1月—2023年7月拟于东台市中医院行外科手术治疗的200例肺部结节性病变患者作为研究对象。对研究对象的切除组织进行病理分析,并分析各类型肺部结节性病变的大体及影像学表现。结果:在200例患者中,良性病变10例(5.00%),良性肿瘤15例(7.50%),前驱腺体病变16例(8.00%),恶性肿瘤159例(79.50%)。恶性肿瘤中浸润性腺癌(包含微浸润性腺癌)127例(79.87%),占比最高,其次为鳞状细胞癌22例(13.84%),小细胞癌8例(5.03%)。前驱腺体病变质地软于良性病变、良性肿瘤、恶性肿瘤,差异有统计学意义(P<0.05);良性肿瘤边界不清占比低于良性病变,前驱腺体病变边界不清占比高于良性肿瘤,恶性肿瘤边界不清占比高于良性病变与良性肿瘤,差异有统计学意义(P<0.05)。结论:肺部结节性病变类型较多,在对肺部结节性病变进行病理诊断时,应结合大体检查、影像学表现及病理特征等综合评估肺结节的良恶性。Objective:To analyze the clinical and pathological manifestations of pulmonary nodular lesions.Methods:A total of 200 patients with pulmonary nodular lesions were selected for surgical treatment in Dongtai Hospital of Chinese Medicine from January 2016 to July 2023.Pathological analysis was performed on the resected tissues of the subjects,and the general and imaging findings of various types of pulmonary nodular lesions were analyzed.Results:Among the 200 patients,there were 10 benign lesions(5.00%),15 benign tumors(7.50%),16 prodromal gland lesions(8.00%)and 159 malignant tumors(79.50%).Among the malignant tumors,invasive adenocarcinoma(including microinvasive adenocarcinoma)accounted for the highest proportion in 127 cases(79.87%),followed by squamous cell carcinoma 22 cases(13.84%)and small cell carcinoma 8 cases(5.03%).The texture of prodromal gland lesions was softer than benign lesions,benign tumors and malignant tumors,and the difference was statistically significant(P<0.05).The proportion of borderline ambiguity in benign tumors was lower than that in benign lesions,the proportion of borderline ambiguity in prodromal gland lesions was higher than that in benign tumors,and the proportion of borderline ambiguity in malignant tumors was higher than that in benign lesions and benign tumors,the difference was statistically significant(P<0.05).Conclusion:There are many types of pulmonary nodular lesions.In the pathological diagnosis of pulmonary nodular lesions,the benign and malignant pulmonary nodules should be comprehensively evaluated in combination with gross examination,Imaging findings and pathological features.

关 键 词：肺部结节性病变 病理分析 大体检查 影像学表现 

分 类 号：R734.2[医药卫生—肿瘤]