等离子射频消融术与CO_(2)激光治疗早期声门型喉癌的效果比较  

Comparison of the effects of plasma radiofrequency ablation and CO_(2) laser in the treatment of early glottic carcinoma

作　　者：洪伟 刘慧娟 苏武 HONG Wei;LIU Huijuan;SU Wu(Department of Otolaryngology,Shangrao People’s Hospital,Shangrao 334000,Jiangxi,China)

机构地区：[1]上饶市人民医院耳鼻咽喉科,江西上饶334000

出　　处：《癌症进展》2024年第4期385-388,共4页Oncology Progress

基　　金：江西省卫生健康委科技计划项目(20202102)。

摘　　要：目的比较等离子射频消融术与CO_(2)激光治疗早期声门型喉癌(EGC)的效果。方法根据治疗方法的不同将80例EGC患者分为对照组(n=40,CO_(2)激光)与研究组(n=40,等离子射频消融术),比较两组患者的围手术期指标[手术时间、术中出血量、术后住院时间、术后24 h视觉模拟评分法(VAS)评分]、嗓音功能[振幅微扰、谐噪比(HNR)、基频微扰]、生活质量[嗓音障碍指数(VHI)]、吞咽功能[电视透视吞咽功能检查(VFSS)]、局部复发情况及并发症发生情况。结果研究组患者手术时间、术后住院时间均明显短于对照组,术中出血量明显少于对照组,术后24 h VAS评分明显低于照组,差异均有统计学意义(P﹤0.01)。术后4周,两组患者HNR均高于本组术前,基频微扰、振幅微扰均低于本组术前,研究组患者HNR高于对照组,基频微扰、振幅微扰均低于对照组,差异均有统计学意义(P﹤0.05)。术后6个月,两组患者VHI评分均低于本组术前,VFSS评分均高于本组术前,研究组患者VHI评分低于对照组,VFSS评分高于对照组,差异均有统计学意义(P﹤0.05)。研究患者的局部复发率和并发症总发生率均低于对照组,但差异均无统计学意义(P﹥0.05)。结论与CO_(2)激光相比,等离子射频消融术治疗EGC的效果更好,可以缩短手术时间,减少术中出血量,减轻术后疼痛感,同时对患者嗓音、吞咽功能的影响较小,可以促进患者术后快速康复,并且提高生活质量。Objective To compare the effects of plasma radiofrequency ablation and CO_(2) laser in the treament of early glottic carcinoma(EGC).Method A total of 80 EGC patients were divided into the control group(n=40,CO_(2) laser)and the study group(n=40,plasma radiofrequency ablation)according to the different treatment methods.The perioperative period indexes[operation time,intraoperative blood loss,postoperative hospital stay,and 24 h visual analogue scale(VAS)score after surgery],voice function[shimmer,harmonic to noise ratio(HNR),jitter],quality of life[voice handicap index(VHI)],swallowing function[video fluoroscopic swallowing study(VFSS)],incidence of local recurrence and complications of the two groups were compared.Result The operation time,postoperative hospital stay in the study group were significantly shorter than those in the control group,intraoperative blood loss was significantly less than that in the control group,and 24 h VAS score after surgery was significantly lower than that in the control group,and the differences were statistically significant(P<0.01).Four weeks after surgery,the HNR in the two groups were higher than those before surgery,jitter and shimmer were lower than those before surgery,the HNR in the study group was higher than that in the control group,jitter and shimmer were lower than those in the control group,and the differences were statistically significant(P<0.05).Six months after surgery,the VHI scores in the two groups were lower than those before surgery,the VFSS scores in the two groups were higher than those before surgery,the VHI score in the study group was lower than that in the control group,VFSS score in the study group was higher than that in the control group,and the differences were statistically significant(P<0.05).The local recurrence rate and total incidence of complications in the study group were lower than those in the control group,but the differences were not statistically significant(P>0.05).Conclusion Compared with CO_(2) laser,plasma radiofrequency ablation

关 键 词：早期声门型喉癌 CO_(2)激光 等离子射频消融术 治疗效果 

分 类 号：R739.65[医药卫生—肿瘤]