合成MRI对腮腺肿瘤性病变的鉴别诊断价值  

Value of synthetic MRI in the differential diagnosis of parotid gland tumors

作　　者：张赞霞 李淑健[1] 张勇[1] 汪卫建 宋曼莉 王文豪 文宝红[1] 程敬亮[1] ZHANG Zanxia;LI Shujian;ZHANG Yong;WANG Weijian;SONG Manli;WANG Wenhao;WEN Baohong;CHENG Jingliang(Department of Magnetic Resonance,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院磁共振科,河南郑州450052

出　　处：《实用放射学杂志》2024年第3期361-364,共4页Journal of Practical Radiology

基　　金：工信部2020年产业技术基础公共服务平台——面向人工智能领域的公共服务平台建设项目(2020-0103-3-1)。

摘　　要：目的探讨基于合成MRI技术的定量弛豫参数在鉴别腮腺常见肿瘤中的应用价值.方法回顾性分析经病理确诊为腮腺肿瘤的59例患者的常规MRI和合成MRI影像资料,在T1、T2和质子密度(PD)图上测量肿瘤全域的T1、T2和PD值.比较各定量弛豫参数在腮腺多形性腺瘤、Warthin瘤和腮腺恶性肿瘤间的差别,采用受试者工作特征(ROC)曲线和DeLong检验评估和比较各定量弛豫参数的诊断效能.结果腮腺多形性腺瘤的T2值大于腮腺恶性肿瘤(P<0.05),腮腺多形性腺瘤和腮腺恶性肿瘤的T1值、T2值和PD值均大于腮腺Warthin瘤(P<0.05).T2值鉴别腮腺多形性腺瘤和腮腺恶性肿瘤的曲线下面积(AUC)为0.794;T1值鉴别腮腺Warthin瘤和腮腺恶性肿瘤的AUC(0.939)高于T2值(0.873,P=0.341)和PD值(0.927,P=0.891),但差异无统计学意义;T2值鉴别腮腺多形性腺瘤和腮腺Warthin瘤的AUC(0.968)高于T1值(0.931,P=0.360)和PD值(0.876,P=0.120),但差异无统计学意义.结论基于合成MRI技术的定量弛豫参数有助于鉴别腮腺多形性腺瘤、Warthin瘤和腮腺恶性肿瘤.Objective To investigate the application value of quantitative relaxation parameters based on synthetic MRI technology in the differential diagnosis of parotid gland tumors.Methods Conventional MRI and synthetic MRI data of 59 patients with patho-logically confirmed parotid gland tumors were analyzed retrospectively.T1,T2,and proton density(PD)values of the tumor were extracted from T1,T2 and PD mapping.The differences in quantitative relaxation parameters of pleomorphic adenomas,Warthin tumors,and malignant tumors were further compared.Diagnostic performance of each quantitative relaxation parameter was assessed and com-pared via receiver operating characteristic(ROC)curve and DeLong test.Results T2 value was significantly higher in pleomorphic adenomas than that in malignant tumors(P<0.05).The T1,T2,and PD values of pleomorphic adenomas and malignant tumors were significantly higher than those of Warthin tumors(P<0.05).The area under the curve(AUC)of the T2 value in differentia-ting pleomorphic adenomas from malignant tumors was 0.794.The AUC for T1 value(0.939)in differentiating Warthin tumors from malignant tumors was significantly higher than that of T2(0.873,P=0.341)and PD(0.927,P=0.891)values,without sta-tistically significant difference.The AUC for T2 value(0.968)in differentiating pleomorphic adenomas from Warthin tumors was significantly higher than that of T1(0.931,P=0.360)and PD(0.876,P=0.120)values,without statistically significant difference.Conclusion Quantitative relaxation parameters based on synthetic MRI technology may contribute to differentiating pleomorphic adenomas,Warthin tumors,and malignant tumors of the parotid gland.

关 键 词：腮腺肿瘤 磁共振成像 鉴别诊断 

分 类 号：R739.91[医药卫生—肿瘤] R445.2[医药卫生—临床医学]