定量图谱MRI序列在预测早期宫颈癌淋巴血管间隙浸润状态中的应用  

Application of MRI compilation sequence for predicting lymphovascular space invasion status in early cervical cancer

作　　者：黄泽波 唐文伟[1] 姚尧 梁童 田忠甫 王莉莉 顾海磊 HUANG Zebo;TANG Wenwei;YAO Yao;LIANG Tong;TIAN Zhongfu;WANG Lili;GU Hailei(Department of Radiology,Women's Hospital of Nanjing Medical University,Nanjing Maternity and Child Health Care Hospital,Nanjing 210004,China)

机构地区：[1]南京医科大学附属妇产医院(南京市妇幼保健院)放射科,江苏南京210004

出　　处：《实用放射学杂志》2024年第3期422-425,429,共5页Journal of Practical Radiology

摘　　要：目的评估定量图谱磁共振成像(MAGiC)序列预测早期宫颈癌淋巴血管间隙浸润(LVSI)的价值.方法回顾性收集经病理证实为宫颈癌的48例患者资料,根据术后病理结果分为LVSI阳性组(n=29)及LVSI阴性组(n=19).注射对比剂前获得MAGiC序列图像,沿着病灶最大层面边缘勾画感兴趣区(ROI),软件自动生成T1、T2和质子密度(PD)值.通过单因素分析筛选预测因素,绘制受试者工作特征(ROC)曲线评估其预测宫颈癌LVSI的诊断效能.结果LVSI阳性组和LVSI阴性组的T1值和PD值有显著差异(P=0.003,P=0.017).2组T2值则无显著差异(P=0.414).T1值和PD值预测LVSI状态的曲线下面积(AUC)分别为0.73,0.721.结论基于MAGiC序列的T1值和PD值在宫颈癌LVSI阳性组中低于LVSI阴性组.MAGiC序列对预测早期宫颈癌LVSI状态有一定的应用价值.Objective To assess the value of magnetic resonance imaging compilation(MAGiC)sequence in predicting lympho-vascular space invasion(LVSI)in early cervical cancer.Methods The data of 48 patients with cervical cancer confirmed by pathology were collected retrospectively,and classified into LVSI-positive group(n=29)and LVSI-negative group(n=19)according to postop-erative pathological results.MAGiC sequence images of patients were obtained before injecting contrast agents,then the region of interest(ROI)was delineated along the largest dimension edge of the lesion,and T1,T2 and proton density(PD)values were automatically generated by the software.Predictors were screened by univariate analysis and receiver operating characteristic(ROC)curves were drawn to assess their diagnostic efficacy for predicting LVSI in cervical cancer.Results Significant differences were found in T1 and PD values between LVSI-positive and LVSI-negative groups(P=0.003,P=0.017).There were no significant differences in T2 values between the two groups(P=0.414).The area under the curve(AUC)for T1 and PD values to predict LVSI status were 0.73 and 0.721,respectively.Conclusion LVSI-positive group of cervical cancer has lower T1 and PD values than LVSI-negative group based on MAGiC sequence.The MAGiC sequence has a certain application value for predicting LVSI status in early cervical cancer.

关 键 词：宫颈癌 定量图谱磁共振成像集合 淋巴血管间隙浸润 

分 类 号：R737.33[医药卫生—肿瘤] R445.2[医药卫生—临床医学]