-PRCD联合APD对急性重症胰腺炎患者预后的影响  

Effect of PRCD combined with APD on prognosis of patients with acute severe pancreatitis

作　　者：王保雨 张会杰 陈国营 Wang Bao-yu;Zhang Hui-jie;Chen Guo-ying(Emergency Department,Luoyang Renda Hospital,Luoyang 471000,Henan,China;Department of Respiratory Medicine,Luoyang Renda Hospital,Luoyang 471000,Henan,China)

机构地区：[1]洛阳仁大医院急诊科,河南洛阳471000 [2]洛阳仁大医院呼吸内科,河南洛阳471000

出　　处：《四川生理科学杂志》2024年第4期861-863,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:分析超声引导经皮腹膜后穿刺置管引流(Percutaneous retroperitoneal catheter drainage,PRCD)联合腹腔穿刺引流(Abdominal paracentesis drainage,APD)对急性重症胰腺炎(Severe acute pancreatitis,SAP)患者预后的影响。方法:回顾性分析2021年03月至2022年09月期间本院急诊科诊治的92例SAP患者临床资料,依据治疗方式不同分为对照组(单纯PRCD,49例)和研究组(PRCD联合APD,43例)。治疗前、治疗后(48~72 h)分别采用酶速率法、血液分析仪计数法、酶联免疫吸附试验测定两组血淀粉酶、白细胞计数(White blood cell,WBC)、C反应蛋白(C reactive protein,CRP)水平,同时记录两组治疗情况、临床相关指标以及感染情况。结果:研究组的血淀粉酶、WBC、CRP水平均显著低于对照组(P<0.05)。研究组体温恢复正常、抗生素使用及重症监护室(Intensive care unit,ICU)住院时间均显著短于对照组,医疗费用显著低于对照组(P<0.05)。研究组多器官功能衰竭、急性呼吸窘迫综合征、多器官功能障碍综合征发生率、死亡率均显著低于对照组(P<0.05);研究组的并发感染率与对照组比较差异无统计学意义(P>0.05)。结论:超声引导下PRCD与APD联合可有效改善SAP患者的预后,不增加其感染发生风险。Objective:To analyze ultrasound-guided Percutaneous retroperitoneal drainage(PRCD)combined with Abdominal paracentesis drainage(PRCD).pancreatitis(APD)in patients with Severe acute pancreatitis(SAP).Methods:Clinical data of 92 SAP patients treated and treated in the emergency department of our hospital from March 2021 to September 2022 were retrospectively analyzed,and were divided into control group(PRCD alone,49 cases)and study group(PRCD combined with APD,43 cases)according to different treatment methods.The levels of amylase,White blood cell(WBC)and C reactive protein(CRP)in blood of the two groups were measured by enzyme rate method,blood analyzer method and enzyme-linked immunosorbent assay before and after treatment(48-72 h),respectively.The treatment status,clinical indicators and infection status of the two groups were recorded simultaneously.Results:The levels of amylase,WBC and CRP in the study group were significantly lower than those in the control group(P<0.05).Normal body temperature,antibiotic use and length of stay in Intensive care unit(ICU)in the study group were significantly shorter than those in the control group,and medical expenses were significantly lower than those in the control group(P<0.05).The incidence and mortality of multiple organ failure,acute respiratory distress syndrome and multiple organ dysfunction syndrome in the study group were significantly lower than those in the control group(P<0.05).There was no significant difference in co-infection rate between the study group and the control group(P>0.05).Conclusion:The combination of PRCD and APD under ultrasound guidance can effectively improve the prognosis of SAP patients without increasing the risk of infection.

关 键 词：超声引导 经皮腹膜后穿刺置管引流 腹腔穿刺引流 急性重症胰腺炎 预后 

分 类 号：R576[医药卫生—消化系统]