内镜下碘染色在早期食管癌及癌前病变诊断中的应用效果  

Application Effect of Endoscopic Iodine Staining in the Diagnosis of Early Esophageal Cancer and Precancerous Lesions

作　　者：许莹[1] 高成城[1] Xu Ying;Gao Chengcheng(Department of Gastroenterology,Huai'an First Hospital Affiliated to Nanjing Medical University,Nanjing 223300,Jiangsu Province,China)

机构地区：[1]南京医科大学附属淮安第一医院消化内科,江苏南京223300

出　　处：《中外医药研究》2024年第5期150-152,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探讨内镜下碘染色在早期食管癌及癌前病变诊断中的应用效果。方法:选取2022年1月—2023年3月南京医科大学附属淮安第一医院收治的疑似早期食管癌或癌前病变患者40例作为研究对象,患者均采用电子上消化道内镜完成食管内镜检查及取样,观察碘染色效果。统计患者术后病理诊断结果,以术后病理诊断结果为“金标准”,统计碘染色诊断早期食管癌及癌前病变的灵敏度、特异度、准确度。结果:术后病理组织学检查确诊早期食管癌患者16例,慢性炎性反应患者5例,低级别上皮内瘤变(lowgradeintraepithelialneoplasia,LGIN)患者14例,高级别上皮内瘤变(highgradeintraepithelialneoplasia,HGIN)患者5例。碘染色诊断早期食管癌的灵敏度为87.50%,特异度为95.83%,准确度为92.50%。碘染色诊断食管LGIN的灵敏度为92.86%,特异度为92.31%,准确度为92.50%。碘染色诊断食管HGIN的灵敏度为80.00%,特异度为94.29%,准确度为92.50%。结论:内镜下碘染色在早期食管癌及癌前病变中诊断效能较好,可有效发现病变,为临床诊疗提供可靠资料。Objective:To investigate the application effect of endoscopic iodine staining in the diagnosis of early esophageal cancer and precancerous lesions.Methods:Forty patients with suspected early esophageal cancer or precancerous lesions admitted to Huai'an First Hospital Affiliated to Nanjing Medical University from January 2022 to March 2023 were selected as the study subjects,and the patients were all used to complete esophageal endoscopy and sampling by electronic upper gastrointestinal endoscopy to observe the effect of iodine staining.Postoperative pathological diagnosis of the patients were analyzed,the sensitivity,specificity and accuracy of iodine staining in the diagnosis of early esophageal cancer and precancerous lesions were calculated using the postoperative pathological diagnostic results of the patients as the"gold standard".Results:Sixteen patients with early esophageal cancer and five patients with chronic inflammatory reaction were diagnosed by postoperative histopathologic examination,there were fourteen patients with low grade intraepithelial neoplasia(LGIN)and five patients with high grade intraepithelial neoplasia(HGIN).The sensitivity of iodine staining for diagnosing early esophageal cancer was 87.50%,the specificity was 95.83%,and the accuracy was 92.50%.The sensitivity of iodine staining for diagnosing esophageal LGIN was 92.86%,the specificity was 92.31%,and the accuracy was 92.50%.The sensitivity of iodine staining in diagnosing esophageal HGIN was 80.00%,specificity was 94.29%,and accuracy was 92.50%.Conclusion:Endoscopic iodine staining has better diagnostic efficacy in early esophageal cancer and precancerous lesions,which can effectively detect lesions and provide reliable information for clinical diagnosis and treatment.

关 键 词：内镜 碘染色 早期食管癌 癌前病变 

分 类 号：R735.1[医药卫生—肿瘤]