连翘饮片及其标准汤剂、挥发油包合物中挥发性成分分析  

Analysis of volatile components in forsythia decoction piece and its standard decoction,volatile oil inclusion compounds

作　　者：高晗 李妍 田方 李雪利 GAO Han;LI Yan;TIAN Fang;LI Xueli(Shineway Pharmaceutical Group Co.,Ltd,Shijiazhuang,Hebei 051430,China;Yunnan Shineway Spirin Pharmaceutical Co.,Ltd,Chuxiong,Yunnan 675000,China;School of Foreign Languages,Tangshan University,Tangshan,Hebei 063000,China)

机构地区：[1]神威药业集团有限公司,河北石家庄051430 [2]云南神威施普瑞药业有限公司,云南楚雄675000 [3]唐山学院外国语学院,河北唐山063000

出　　处：《现代医药卫生》2024年第8期1272-1276,共5页Journal of Modern Medicine & Health

基　　金：云南省科学技术厅重大科技专项计划项目(202102AA310027);云南省科学技术厅科技计划项目(2019ZF008)。

摘　　要：目的探讨连翘饮片及其标准汤剂、挥发油包合物中挥发性成分的差异。方法采用气相色谱-离子迁移谱法测定连翘饮片及其标准汤剂、挥发油包合物中挥发性成分并进行相关分析。结果共检测出14种挥发性成分,并定性了3种成分,分别为α-蒎烯、柠檬烯、芳樟醇。连翘饮片与连翘挥发油中挥发性成分基本一致,与连翘提取液有差异。连翘标准汤剂与连翘挥发油包合物中挥发性成分保持一致。结论连翘挥发油包合物与连翘挥发油成分存在差异,但与连翘标准汤剂基本一致,可为连翘配方颗粒生产、质量控制提供参考。Objective To explore the differences of volatile components in forsythia decoction pieces,its standard decoction and volatile oil inclusion compounds.Methods The volatile components in forsythia decoction pieces and its standard decoction and volatile oil inclusion compounds were determined by gas chromatography-ion migration spectrometry.Results A total of 14 volatile compounds were detected and three were identified,namely α-pinene,limonene and linalool.The volatile components of forsythia decoction pieces and volatile oil of forsythia were basically the same,but different from forsythia extract.The standard decoction of forsythia was consistent with the volatile components in the inclusion compound of forsythia volatile oil.Conclusion The composition of the inclusion compound of forsythia volatile oil is different from that of forsythia volatile oil,but it is basically the same as that of forsythia standard decoction,which can provide reference for the production and quality control of forsythia formula granules.

关 键 词：连翘 挥发性成分 气相色谱-离子迁移谱法 Α-蒎烯 

分 类 号：R284.2[医药卫生—中药学]