精神心理因素在口臭发病机制中的相关性研究进展  

Research progress on psychological factors in the pathogenesis of halitosis

作　　者：李聪聪 赵曼[1] 刘传霞 Li Congcong;Zhao Man;Liu Chuanxia(Dept.of General Dentistry,Stomatology Hospital,Zhejiang University School of Medicine&Zhejiang University School of Stomatology&Zhejiang Provincial Clinical Research Center for Oral Diseases&Key Laboratory of Oral Biomedical Research of Zhejiang Province&Cancer Center of Zhejiang University&Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province,Hangzhou 310000,China;Dept.of Oral Medicine,Stomatology Hospital,Zhejiang University School of Medicine&Zhejiang University School of Stomatology&Zhejiang Provincial Clinical Research Center for Oral Diseases&Key Laboratory of Oral Biomedical Research of Zhejiang Province&Cancer Center of Zhejiang University&Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province,Hangzhou 310000,China)

机构地区：[1]浙江大学医学院附属口腔医院口腔综合科、浙江大学口腔医学院、浙江省口腔疾病临床医学研究中心、浙江省口腔生物医学研究重点实验室、浙江大学癌症研究院、口腔生物材料与器械浙江省工程研究中心,杭州310000 [2]浙江大学医学院附属口腔医院口腔黏膜病科、浙江大学口腔医学院、浙江省口腔疾病临床医学研究中心、浙江省口腔生物医学研究重点实验室、浙江大学癌症研究院、口腔生物材料与器械浙江省工程研究中心,杭州310000

出　　处：《国际口腔医学杂志》2024年第3期368-373,共6页International Journal of Stomatology

摘　　要：口臭在人群中一直有着较高的发病率,影响着世界上近一半的人口。随着人们的卫生意识提高,它成为人们社会交往中愈发关注和在意的问题。研究发现心理因素与口臭的发生发展有着较为密切的联系,焦虑、抑郁等负性情绪可能直接引起妄想性口臭的发病,同时它们也可以通过影响口腔菌群、牙周炎、唾液、免疫功能及系统性疾病等方面间接促进口内挥发性硫化物的生成。本文就近年来精神心理因素在口臭发病机制中的直接和间接相关性的研究进展作进行综述,以期提高临床医生的认识,对口臭患者的临床诊疗起到一定的启示作用。Halitosis has always been prevalent in humans,affecting nearly half of the world's population.With the improvement of people’s health awareness,it has recently become a health concern among the public.Studies have shown that psychological factors were closely related to the occurrence and development of halitosis.Negative emotions such as anxiety and depression might directly lead to delusional halitosis while indirectly promoting the generation of volatile sulfur compounds in the oral cavity through affecting oral microbiota,periodontitis,saliva,immune function,and systemic diseases.This article provides a summary of research on direct and indirect correlations on the psychological factors in the pathogenesis of halitosis in recent years to improve the understanding of clinical doctors and provide some inspiration for the clinical diagnosis and treatment of patients with halitosis in the future.

关 键 词：口臭 精神心理因素 负性情绪 口腔微环境 硫化物 

分 类 号：R781.9[医药卫生—口腔医学]