儿童C型淋巴瘤样丘疹病一例  

Type C lymphomatoid papulosis in a child:a case report

作　　者：杨远远 刘霞 索翠平 管志强 李永欣 赵建斌 YANG Yuanyuan;LIU Xia;SUO Cuiping;GUAN Zhiqiang;LI Yongxin;ZHAO Jianbin(Department of Dermatology,Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University,Xuzhou 221000,China;Department of Pathology,Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University,Xuzhou 221000,China;Department of Medical Records and Data Statistics Center,Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University,Xuzhou 221000,China)

机构地区：[1]徐州医科大学附属市立医院皮肤科,江苏徐州221000 [2]徐州医科大学附属市立医院病理科,江苏徐州221000 [3]徐州医科大学附属市立医院病案与数据统计中心,江苏徐州221000

出　　处：《中国麻风皮肤病杂志》2024年第6期427-429,共3页China Journal of Leprosy and Skin Diseases

摘　　要：C型淋巴瘤样丘疹病较少见,本文报道一例。患者,男,13岁。全身反复红色丘疹结节2年,部分皮疹中央溃烂,系统检查未见异常,曾诊断为“急性痘疮样苔藓样糠疹”。入院后完善组织病理示:肿瘤真皮层和皮下组织可见形态一致的间变大淋巴细胞弥漫浸润。免疫组化:CD2(+++),CD8(+),CD30(+++),GranzymeB(+),Ki67(+90%),TI-A(+),TCR基因重排阳性。诊断:C型淋巴瘤样丘疹病。Type C lymphomatoid papulosis is rare,herein we report a case in this paper.A 13-year-old boy presented with recurrent red papular nodules all over the body for 2 years,with partial nodules breaking down in the central.Physical examination showed no abnormalities,and he was early diagnosed as pityriasis lichenoides et varioliformis acuta.Histopathological biopsy showed diffuse infiltration of large anaplastic lymphocytes with consistent morphology in the dermis and subcutaneous tissue of the tumor.Immunohistochemical showed CD2(+++),CD8(+),CD30(+++),GranzymeB(+),Ki67(+90%),TI-A(+),test positive for TCR gene rearrangement.The dignosis of type C lymphomatoid papulosis was finally made.

关 键 词：淋巴瘤样丘疹病 儿童 免疫组织化学 

分 类 号：R739.5[医药卫生—肿瘤]