药师干预在BZDs患者戒断治疗期间的应用效果  

Application Effect of Pharmacist Intervention During Withdrawal Treatment of BZDs Patients

作　　者：武芳[1] 张鑫 罗瑾[1] 马春燕 赵娟[1] 吴建华[2] WU Fang;ZHANG Xin;LUO Jin;MA Chunyan;ZHAO Juan;WU Jianhua(Department of Pharmacy,Urumqi Fourth People's Hospital,Urumqi 830001,Xinjiang,China;Department of Pharmacy,People's Hospital of Xinjiang Uygur Autonomous Region,Uygur 830001,Xinjiang,China)

机构地区：[1]乌鲁木齐市第四人民医院药剂科,新疆乌鲁木齐830001 [2]新疆维吾尔自治区人民医院药剂科,新疆乌鲁木齐830001

出　　处：《中国药物滥用防治杂志》2024年第3期410-412,417,共4页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：乌鲁木齐市卫生健康委科技计划项目(编号:202126)。

摘　　要：目的:探讨药师干预BZDs患者戒断治疗中的应用效果。方法:收集2021年8月—2022年8月乌鲁木齐市第四人民医院收治的160例使用BZDs药物住院患者,随机分为对照组和实验组,每组80例。对照组采用常规干预,观察组给予药师干预。比较两组药物依赖发生率和预后疾病转归效果。结果:实验组第1周、第3周、第4周时药物依赖评分均低于对照组,差异有统计学意义(P<0.05);实验组临床有效率为96.25%,高于对照组的83.75%,差异有统计学意义(P<0.05)。结论:临床药师在使用BZDs患者中开展药师干预,对降低药物依赖发生率,实现疾病转归等具有极高的可行性,可为临床合理用药提供实验依据。Objective:To explore the application effect of pharmacist intervention in withdrawal treatment of BZDs patients.Methods:A total of 160 inpatients treated with BZDs in the Fourth People's Hospital of Urumqi from August 2021 to August 2022 were collected and randomly divided into control group and experimental group,with 80 inpatients in each group.The control group was given routine intervention,and the observation group was given pharmacist intervention.The incidence of drug dependence and prognosis of disease outcome were compared between the two groups.Results:The drug dependence scores of the experimental group were lower than those of the control group at the first week,the third week and the fourth week,and the difference was statistically significant(P<0.05).The clinical effective rate of the experimental group was 96.25%,which was higher than 83.75% of the control group,and the difference was statistically significant(P<0.05).Conclusion:Clinical pharmacists intervention in patients with BZDs is highly feasible to reduce the incidence of drug dependence and achieve disease outcome,which can provide experimental basis for clinical rational drug use.

关 键 词：临床药师 苯二氮[艹卓]类 药物依赖 戒断 

分 类 号：R749.64[医药卫生—神经病学与精神病学]