益气聪明汤对智力障碍患儿智力发育水平及日常生活能力的影响  

Effect of Yiqi Congming Decoction(益气聪明汤)on Intellectual Development Level and Daily Living Ability of Children with Intellectual Disability

作　　者：李刚 李晓凤 付晓翔 杨鹏飞 LI Gang;LI Xiaofeng;FU Xiaoxiang;YANG Pengfei(Linyi Disabled Persons Rehabilitation Service Cente,Linyi 276023,Shandong,China;Children's Health Department of Linyi Maternal and Child Health Hospital,Linyi 276000,Shandong,China)

机构地区：[1]临沂市残疾人康复服务中心,山东临沂276023 [2]临沂市妇幼保健院,山东临沂276000

出　　处：《实用中医内科杂志》2024年第4期105-108,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：临沂市妇幼保健院科研基金项目(Y2021MS06)。

摘　　要：目的探究益气聪明汤对智力障碍患儿智力发育及日常生活能力的影响。方法选取2019年10月—2022年10月医院收治的158智力障碍患儿作为本次研究对象,依照随机数字表法进行分组,观察组、对照组各79例。对照组:针刺治疗。观察组:对照组基础上实施益气聪明汤治疗。治疗12周。比较治疗后总有效率、智力发育水平、日常生活能力、运动功能评分、DA、NE、NSE、5-HT水平。结果治疗后观察组总有效率显著高于对照组,P<0.05;治疗前两组智力发育水平无差异,差异无统计学意义(P>0.05),治疗后两组智力发育水平评分升高,且观察组智力发育水平评分高于对照组,差异有统计学意义(P<0.05)。治疗前两组日常生活能力无差异,差异无统计学意义(P>0.05),治疗后两组日常生活能力评分明显增加,且观察组日常生活能力评分高于对照组,差异有统计学意义(P<0.05)。治疗前两组运动功能无差异,差异无统计学意义(P>0.05),治疗后两组运动功能评分明显增加,且观察组运动功能评分高于对照组,差异有统计学意义(P<0.05)。治疗前两组DA、NE、NSE、5-HT水平比较无差异,差异无统计学意义(P>0.05),治疗后两组DA、NE、NSE、5-HT水平均显著变化,DA、NE、5-HT水平明显增加,NSE显著降低,且与对照组相比,观察组DA、NE、5-HT水平较高,NSE水平较低,差异有统计学意义(P<0.05)。结论益气聪明汤对智力障碍患儿有良好的治疗效果,能够显著提升患儿智力发育水平、日常生活能力及运动功能,对血清神经递质水平有良好的调节作用。Objective To explore the effects of Yiqi Congming Decoction(益气聪明汤)on intellectual development and daily living ability of children with intellectual disability.Methods A total of 158 children with intellectual disability admitted to the hospital from October 2019 to October 2022 were selected as the objects of this study and were divided into groups according to random number table method,with 79 cases in the observation group and 79 cases in the control group.The control group used the acupuncture treatment.The observation group additionally used Yiqi Congming Decoction.The treatment lasted for 12 weeks.The total effective rate,intellectual development level,ability of daily living,motor function score,the levels of dopamine(DA),norepinephrine(NE),neuron-specific enolase(NSE)and 5-hydroxytryptamine(5-HT)were compared after treatment.Results After treatment,the overall effective rate of the observation group was significantly greater than that of the control group(P<0.05).Before treatment,there was no difference in the levels of intellectual growth of the two groups(P>0.05).After treat-ment,the difference in intellectual development scores between the two groups increased,with the observation group scoring higher than the control group.The difference was statistically significant(P<0.05).There was no significant difference in daily living capacity between the two groups before treatment(P>0.05).After treatment,the difference in daily living capacity between the two groups increased dramatically,and the score of the observation group was greater than that of the control group,with a statisti-cally significant difference(P<0.05).There was no statistically significant difference in motor function between the two groups before treatment(P>0.05),and the motor function score of the two groups increased significantly after treatment,with the obser-vation group having a higher motor function score than the control group(P<0.05).Before treatment,there was no significant change in DA,NE,NSE or 5-HT between the tw

关 键 词：智力障碍 益气聪明汤 智力发育 日常生活能力 

分 类 号：R277.7[医药卫生—中医学]