垂体细胞瘤2例并文献复习  

Pituicytoma:2 cases and literature review

作　　者：李政[1] 牛朝诗 梅加明 王宣之 陈鹏[1] Li Zheng;Niu Chaoshi;Mei Jiaming;Wang xuanzhi;Chen Peng(Department of Neurosurgery,the First Af filiated Hospital of University of Science and Technology of China,Anhui Provincial Hospital,Hefei,23000l,Anhui,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)神经外科,合肥230001

出　　处：《立体定向和功能性神经外科杂志》2024年第1期48-53,共6页Chinese Journal of Stereotactic and Functional Neurosurgery

基　　金：安徽省重点研究与开发计划(编号:202104j07020025);安徽省高等学校省级质量工程项目(编号:2021jyxm1778)。

摘　　要：目的探讨垂体细胞瘤的临床表现、影像学表现、病理及治疗方案。方法回顾分析我科2019年1月至2023年10月的2例垂体细胞瘤的临床资料、影像学表现、病理及治疗方案,并复习相关文献。结果2例垂体细胞瘤患者,男女各1例,主要症状有头痛、视力下降,头颅磁共振表现为鞍内、鞍上的等T1、等/稍低T2信号,增强后明显强化的实质性病灶。分别予以显微镜下经鼻蝶入路鞍区病变切除术和神经内镜下经鼻蝶入路鞍区病变切除术。术后病理为垂体细胞瘤(WHO I级),术后均未行放疗治疗。两个病例随访4年、3个月未见复发。结论垂体细胞瘤罕见,容易误诊,肿瘤血供丰富,手术全切是治疗的主要方式。Objective To investigate the clinical and imaging manifestations,pathology and treatment of pituicytoma.Methods The clinical data,imaging findings,pathology and treatment of 2 patients who were diagnosed as pituicytoma in our hospital from January 2019 to October 2023 were retrospectively analyzed,and the relevant literature was reviewed.Results There were 2 patients of pituicytoma,1 male and 1 female.The main symptoms include headache and vision decreased,and the head magnetic resonance imaging showed iso-intense on T1 weighted imaging and hypo-or iso-intense on T2 weighted imaging in and above the sellar region,substantial lesions were increased signal intensity after enhancement.Transnasal sphenoid approach under microscope and neuroendoscope were performed respectively.The postoperative pathology was pituicytoma(WHO Grade I),which was not treated with radiotherapy.Two cases were followed up for 4 years and 3 months without recurrence.Conclusion Pituicytoma is rare and easily misdiagnosed,the blood supply of tumor tissue is affluent,total surgical resection is the main way of treatment.

关 键 词：垂体细胞瘤 诊断 治疗 

分 类 号：R736.4[医药卫生—肿瘤]