感染性腹泻流行趋势的研究进展  

Research progress in epidemic trend of infectious diarrhea

作　　者：孙振璐[1] 刘国胜 赵丽丽 高巧[1] 王雪岩[1] Sun Zhenlu;Liu Guosheng;Zhao Lili;Gao Qiao;Wang Xueyan(Yantai Center for Disease Control and Prevention,Yantai 264003,China;Laizhou Center for Disease Control and Prevention,Laizhou 261400,China)

机构地区：[1]烟台市疾病预防控制中心,烟台264003 [2]莱州市疾病预防控制中心,莱州261400

出　　处：《中华微生物学和免疫学杂志》2024年第3期274-280,共7页Chinese Journal of Microbiology and Immunology

基　　金：山东省烟台市科技计划项目(2017WS119);山东省医务职工科技创新计划项目(SDYWZGKCJH2023043)。

摘　　要：感染性腹泻是由多种病原体引起,广泛存在于世界各地的胃肠道感染性疾病。也是当今全球最重要的公共卫生问题之一,是引起全球5岁以下儿童死亡的第二大原因。感染性腹泻的病原体包含病毒性腹泻病原体、细菌性腹泻病原体和寄生虫相关病原体。而与病毒性腹泻相关的病原体是最主要的诱因,主要有诺如病毒、轮状病毒、星状病毒、札如病毒等。诱发细菌性腹泻的主要病原体有致泻性大肠埃希菌、沙门菌、志贺菌、副溶血弧菌、弯曲菌等。本文针对感染性腹泻的流行趋势、病原谱变化进行综述,目的是掌握我国感染性腹泻的分布及流行特征,为制定防控策略、减轻疾病负担提供参考。Infectious diarrhea is a gastrointestinal infectious disease caused by a wide range of pathogens and found throughout the world.It is one of the most important public health problems in the world and the second leading cause of death among children under five years of age.The pathogens of infectious diarrhea include viral diarrhea pathogens,bacterial diarrhea pathogens,and parasites.Viruses are the most frequent pathogens,mainly including norovirus,rotavirus,astrovirus and sapovirus.The most frequently identified organisms causing bacterial diarrhea are diarrheagenic Escherichia coli,Salmonella,Shigella,Vibrio parahaemolyticus and Campylobacter.This paper provides an overview of the epidemiological trends and changes in the pathogen spectrum of infectious diarrhea for better understanding the distribution and epidemiological features of infectious diarrhea in China,and hopes to provide reference for developing prevention and control strategies and reducing the disease burden.

关 键 词：病原体 感染性腹泻 病原谱 流行特征 

分 类 号：R574.62[医药卫生—消化系统] R181.3[医药卫生—内科学]