Liquid Crystal Based Label-Free Optical Sensors forBiochemical Application  

作　　者：Jieyuan TANG Zhibin LI Mengyuan XIE Yunhan LUO Jianhui YU Guojie CHEN Zhe CHEN 

机构地区：[1]School of Physics and Optoelectronic Engineering,Foshan University,Foshan 528225,China [2]Guangdong-Hong Kong.Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology,Foshan Universiy,Foshan 528225,China [3]Key Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes,Jinan University,Guangzhou 510632.China [4]Department of Optoelectronic Engineering,Jinan University,Guangzhou 510632,China [5]JiHua Laboratory,Foshan 528200,China

出　　处：《Photonic Sensors》2024年第2期57-88,共32页光子传感器（英文版）

基　　金：supported by the National Natural Science Foundation of China (Grant Nos.62105125,62075088,and 12174155);Natural Science Foundation of Guangdong Province (Grant No.2022A1515140055);Research Fund of Guangdong-Hong Kong-Maco Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology (Grant No.2020B1212030010);Guangdong Provincial Key Laboratory of Semiconductor Micro Display (Grant No.2020B121202003);National Key Research and Development Program of China (Grant No.2021YFB2800801);Natural Science Foundation of Guangdong Province for Distinguished Young Scholar (Grant No.2020B1515020024);Key-Area Research and Development Program of Guangdong Province (Grant No.2019B010138004);Guangdong Basic and Applied Basic Research Foundation (Grant No.2021A1515110667);Special Project in Key Fields of the Higher Education Institutions of Guangdong Province (Grant No.2020ZDZX3022).

摘　　要：Biochemical sensors have important applications in biology,chemistry,and medicine.Nevertheless,many biochemical sensors are hampered by intricate techniques,cumbersome procedures,and the need for labeling.In the past two decades,it has been discovered that liquid crystals can be used to achieve the optical amplification of biological interactions.By modifying recognition molecules,a variety of label-free biochemical sensors can be created.Consequently,biochemical sensors based on the amplification of liquid crystals have become one of the most promising sensors.This paper describes in detail the optical sensing principle of liquid crystals,sensing devices,and optical detection technologies.Meanwhile,the latest research findings are elucidated.Finally,the challenges and future research directions are discussed.

关 键 词：Optical sensor BIOCHEMISTRY liquid crystal LABEL-FREE 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]