中医辨证对非小细胞肺癌化疗后疲乏治疗的临床观察  

Clinical observation of traditional Chinese medicine syndrome differentiation on fatigue after chemotherapy for non-small cell lung cancer

作　　者：庞秀 李敏[1] PANG Xiu;LI Min(Third Department of Internal Medicine,Xiyuan hospital of China Academy of Chinese Medical Sciences Jining Hospital(Jining Hospital of Traditional Chinese Medicine),Jining 272000,China)

机构地区：[1]中国中医科学院西苑医院济宁医院(济宁市中医院)内三科,山东济宁272000

出　　处：《医师在线》2024年第4期84-87,共4页Journal of Doctors Online

基　　金：济宁市重点研发计划项目(2021YXNS141)。

摘　　要：目的 研究中医辨证对非小细胞肺癌化疗后疲乏的治疗作用.方法 80例非小细胞肺癌化疗后患者随机分为治疗组40例和对照组40例,两组患者在化疗后运用Piper疲乏评分量表评估疲乏状态,并应用中医证候评分评估中医证候状况.治疗组在中医辨证论治的基础上结合运用补气健脾的中药,对照组给予对症支持治疗.观察对比两组患者中医证候状况、疲乏程度的区别.结果 治疗前,两组中医证候及情感疲乏、行为疲乏、认知疲乏、躯体疲乏比较差异无统计学意义(P>0.05).治疗后,治疗组中医证候改善的程度及情感疲乏、行为疲乏、认知疲乏、躯体疲乏减轻的程度均优于对照组(P<0.05).治疗组总有效率为85.00%,高于对照组的62.50%(P<0.05).结论 中医辨证治疗能改善非小细胞肺癌化疗后中医证候状况,并减轻疲乏的发生程度.Objective To study the therapeutic effect of traditional Chinese medicine(TCM)syndrome differentiation on fatigue after chemotherapy for non-small cell lung cancer.Methods 80 patients with non-small cell lung cancer after chemotherapy were randomly divided into treatment group with 40 cases and control group with 40 cases.The two groups were assessed by the Piper fatigue score Scale after chemotherapy,and the TCM syndrome score was used to evaluate the TCM syndrome status.The treatment group combined with TCM to replenish qi and strengthen the spleen on the basis of syndrome TCM differentiation and treatment,while the control group received symptomatic supportive treatment.The differences in TCM syndrome and fatigue between the two groups were observed.Results Before treatment,there was no significant difference in TCM syndrome,emotional fatigue,behavioral fatigue,cognitive fatigue and physical fatigue between the two groups(P>0.05).After treatment,the degree of improvement of TCM symptoms,emotional fatigue,behavioral fatigue,cognitive fatigue,and physical fatigue in the treatment group was better than those in the control group(P<0.05).The total effective rate of the treatment group was 85.00%,which was higher than 62.50%of the control group(P<0.05).Conclusion TCM syndrome differential therapy can improve the TCM syndrome status of non-small cell lung cancer after chemotherapy and reduce the incidence of fatigue.

关 键 词：非小细胞肺癌 化疗 疲乏 中医辨证论治 

分 类 号：R73[医药卫生—肿瘤]