急性缺血性卒中溶栓后发生出血性转化的危险因素分析  

作　　者：方军钢 陆新宇[1] 

机构地区：[1]江苏大学附属人民医院,江苏镇江212000

出　　处：《浙江临床医学》2024年第4期534-536,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨急性缺血性卒中(AIS)溶栓治疗后发生出血性转化的危险因素。方法收集2020年1月至2022年12月接受rt-PA静脉溶栓AIS患者的临床资料,分为出血转化组(40例)和非出血转化组(223例),采用多因素Logistic回归分析溶栓后发生出血性转化的危险因素。结果多因素Logistic回归分析显示,溶栓前NIHSS评分高(P<0.01)、血糖高(P=0.04)是溶栓后发生出血性转化的独立危险因素。结论溶栓前NIHSS评分高、血糖高与AIS患者静脉溶栓后出现出血性转化有关。Objective To investigate the risk factors of hemorrhagic transformation after thrombolysis in acute ischemic stroke.Methods We collected and analyzed the clinical data of patients with acute ischemic stroke who received rt-PA intravenous thrombolysis in the people's Hospital Affiliated to Jiangsu University from 2020 to 2022.They were divided into the hemorrhagic transformation group(40 cases)and the non-hemorrhagic transformation group(223 cases).Multivariate logistic regression was used to analyze the risk factors of hemorrhagic transformation after thrombolysis.Results Multivariate logistic regression analysis showed that high NIHSS score(P<0.01)and high blood glucose(P=0.04)were risk factors for hemorrhagic transformation after thrombolysis.Conclusion High NIHSS score and high blood glucose before thrombolysis are associated with hemorrhagic transformation after intravenous thrombolysis.

关 键 词：静脉溶栓 出血性转化 NIHSS评分 血糖 

分 类 号：R743.3[医药卫生—神经病学与精神病学]