细菌性阴道病最新诊断及治疗方案的研究进展  

Advances in the latest diagnosis and treatment of bacterial vaginosis

作　　者：艾雯霞 李东慧 亓丁 张倩阁 张明书(综述) 刘丽(审校) AI Wenxia;LI Donghui;QI Ding;ZHANG Qiange;ZHANG Mingshu;LIU Li(Graduate School of Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,China;Graduate School of Heilongjiang Academy of Traditional Chinese Medicine,Harbin,Heilongjiang 150036,China;Hysteroscopy Room,the First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,China)

机构地区：[1]黑龙江中医药大学研究生院,黑龙江哈尔滨150040 [2]黑龙江省中医药科学院研究生院,黑龙江哈尔滨150036 [3]黑龙江中医药大学附属第一医院宫腔镜室,黑龙江哈尔滨150040

出　　处：《检验医学与临床》2024年第9期1326-1331,共6页Laboratory Medicine and Clinic

基　　金：教育部春晖计划合作科研项目(HLJ2019032)。

摘　　要：细菌性阴道病(BV)是一种由阴道优势菌株转变为各种厌氧菌混合物的微生物群失调型疾病,易提高性传播感染、泌尿生殖系统感染、盆腔炎症的易感性和异常妊娠的风险,早期明确BV的病理机制、病原体诊断及正确的治疗方案是有效治疗BV的关键。目前Amsel标准和Nugent评分为BV临床最常用的诊断方法,但其诊断可能受到个人技能和经验的影响,随着新的诊断方法不断推进,如深度学习模型、分子诊断技术、其他新兴战略等,BV的治疗目前仍以阻止BV相关微生物的增殖和恢复正常的阴道微生物群为主。该文综述了细菌性阴道炎的致病机制、临床检验技术及常用治疗方案,为临床治疗该病提供了理论指导,以提高患者的生活质量,具有积极的临床意义。Bacterial vaginosis(BV)is a disease with microbiome disorder that changes from the dominant strain of vagina to a variety of anaerobic bacteria mixture,which is prone to increase the susceptibility of sexually transmitted infections,genitourinary system infections,pelvic inflammation and the risk of abnormal pregnancy.Early identification of the pathological mechanism,pathogen diagnosis and correct treatment plan of BV are the key to effective treatment.Currently,the Amsel criteria and Nugent score are the most commonly used diagnostic methods for BV,but their diagnosis can be influenced by personal skills and experience.As new diagnostic methods continue to advance,such as deep learning models,molecular diagnostic techniques and other emerging strategies,the treatment of BV is still mainly focused on preventing the proliferation of BV-associated microorganisms and restoring normal vaginal flora at present.This article reviews the pathogenic mechanism,clinical testing techniques and common treatment schemes of bacterial vaginitis,which can provide theoretical guidance for clinical treatment of the disease and improve the quality of life of the majority of women,with positive clinical significance.

关 键 词：细菌性阴道病 阴道微生物群落 乳杆菌 非抗菌药物疗法 

分 类 号：R711.3[医药卫生—妇产科学]