胸腔镜支气管袖式成形肺叶切除术治疗中央型小细胞肺癌的效果  

Efficacy of Thoracoscopic Bronchial Sleeve Plastic Lobectomy in the Treatment of Central Small Cell Lung Cancer

作　　者：许潇潇 刘霞[1] 王佳琦 XU Xiaoxiao;LIU Xia;WANG Jiaqi(Thoracic Surgery Department,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院胸外科,河南郑州450000

出　　处：《河南医学研究》2024年第9期1570-1573,共4页Henan Medical Research

摘　　要：目的探讨胸腔镜支气管袖式成形肺叶切除术治疗中央型小细胞肺癌的效果。方法选取2019年1月至2020年5月于郑州大学第一附属医院接受治疗的中央型小细胞肺癌患者82例作为研究对象,分为观察组(接受胸腔镜支气管袖式成形肺叶切除术)与对照组(接受传统手术治疗),各41例。对比患者围手术期相关指标、并发症发生率、生存率、无进展生存时间及复发率。分析视觉模拟评分法(VAS)及Karnofsky功能状态评分(KPS)。结果观察组术中出血量(231.49±23.56)mL、胸腔引流量(902.20±102.39)mL,均少于对照组[(302.17±30.41)mL、(1145.32±172.41)mL],而术后引流时间(6.15±1.41)d、住院时间(11.41±2.49)d短于对照组[(7.10±1.93)d、(13.56±3.24)d](P<0.05);观察组术后并发症发生率、复发率、VAS评分低于对照组,KPS评分高于对照组(P<0.05)。观察组的无进展生存时间长于对照组(P<0.05)。结论胸腔镜支气管袖式成形肺叶切除术治疗有利于降低并发症发生率和延长无进展生存时间。Objective To investigate the efficacy of thoracoscopic bronchial sleeve plastic lobectomy in the treatment of central small cell lung cancer.Methods A total of 82 patients with central small cell lung cancer who received treatment in the First Affiliated Hospital of Zhengzhou University from January 2019 to May 2020 were selected as the study objects,and were divided into the observation group(receiving thoracoscopic bronchoplasty sleeve pulmonary lobotomy)and the control group(receiving traditional surgical treatment),with 41 cases in each group.Perioperative indexes,complication rate,survival rate,progression-free survival time and recurrence rate were compared between the two groups.Visual analogue scale(VAS)and Karnofsky functional status score(KPS)were analyzed.Results The intraoperative blood loss(231.49±23.56)mL and thoracic drainage flow(902.20±102.39)mL in the observation group were less than those in the control group[(302.17±30.41)mL and(1145.32±172.41)mL].The postoperative drainage time(6.15±1.41)days and hospitalization time(11.41±2.49)days were shorter than those in the control group[(7.10±1.93)days and(13.56±3.24)days](P<0.05).The postoperative complication rate,recurrence rate and VAS score in the observation group were lower than those in the control group,and KPS score was higher than those in the control group(P<0.05).The progression-free survival time of observation group was longer than that of control group(P<0.05).Conclusion Thoracoscopic sleeve bronchoplastic pulmonary lobectomy is beneficial to reduce the incidence of complications and prolong progression-free survival.

关 键 词：胸腔镜 支气管袖式 成形肺叶切除术 中央型 小细胞肺癌 疗效 

分 类 号：R734.2[医药卫生—肿瘤]