脑卒中患者继发上消化道出血的现状分析及影响因素研究  

Current status analysis and influencing factors of secondary upper gastrointestinal bleeding in stroke patients

作　　者：王文君[1] 康菊红 王梦茹 WANG Wenjun;KANG Juhong;WANG Mengru(Emergency Center,the First Affiliated Hospital of Xinjiang Medical University,Xinjiang Uygur Autonomous Region,Urumchi830000,China)

机构地区：[1]新疆医科大学第一附属医院急救中心,新疆乌鲁木齐830000

出　　处：《中国医药导报》2024年第8期103-106,共4页China Medical Herald

摘　　要：目的 探讨脑卒中患者继发上消化道出血(UGH)现状及的影响因素。方法 选取2021年1月至2022年8月新疆医科大学第一附属医院收治的脑卒中患者126例,根据UGH发生情况分为UGH组和非UGH组。比较两组一般资料、疾病相关情况。采用多因素logistic回归分析确定脑卒中患者继发UGH的影响因素。结果 126例患者中30例(23.81%)继发UGH。UGH组年龄≥65岁、高血压3级、有既往卒中史、出血性卒中、入院格拉斯哥昏迷评分(GCS)3~8分、使用抗凝药的占比高于非UGH组(P<0.05)。年龄≥65岁(OR=1.472,95%CI:1.093~1.982)、高血压3级(OR=2.209,95%CI:1.387~3.518)、入院时GCS评分3~8分(OR=2.692,95%CI:1.315~5.511)、使用抗凝药(OR=1.608,95%CI:1.125~2.298)是脑卒中患者继发UGH的危险因素(P<0.05)。结论 年龄≥65岁、高血压3级、入院GCS评分3~8分、使用抗凝药是脑卒中患者继发UGH的危险因素。Objective To investigate the status of secondary upper gastrointestinal bleeding(UGH)in stroke patients and the influencing factors.Methods A total of 126 stroke patients admitted to First Affiliated Hospital of Xinjiang Medical University from January 2021 to August 2022 were selected and they were divided into UGH group and non-UGH group according to the occurrence of UGH.Demographic characteristics and disease correlation were compared between two groups.Multivariate logistic regression analysis was used to determine the influencing factors of secondary UGH in stroke patients.Results Among the 126 patients,30(23.81%)had secondary UGH.The proportion of age≥65 years old,hypertension grade 3,previous stroke history,hemorrhagic stroke,glasgow coma scale(GCS)of 3-8 points,use of anticoagulant proportion in UGH group were higher than non-UGH group(P<0.05).Age≥65 years old(OR=1.472,95%CI:1.093-1.982),hypertension grade 3(OR=2.209,95%CI:1.387-3.518),GCS score on admission 3-8(OR=2.692,95%CI:1.315-5.511),use of antic-oagulants(OR=1.608,95%CI:1.125-2.298)were risk factors for UGH in stroke patients(P<0.05).Conclusion Age≥65 years old,hypertension,grade 3 GCS score of 3-8,use of anticoagulants are risk factors for secondary UGH in stroke patients.

关 键 词：脑卒中 上消化道出血 影响因素 胃黏膜 屏障 

分 类 号：R743[医药卫生—神经病学与精神病学]