妊娠期糖尿病孕妇增重状况对焦虑的影响:维生素D水平的中介作用  

Effect of Weight Gain Status on Anxiety in Pregnant Women with Gestational Diabetes Mellitus:the Mediating Role of Vitamin D Levels

作　　者：孙伟欣 李爱玲[2] 温蓉 侯铭[4] 李晓瑞[5] 左彭湘[1] SUN Wei-xin;LI Ai-ling;WEN Rong;HOU Ming;LI Xiao-rui;ZUO Peng-xiang(Shihezi Univerisity School of Medicine,Xinjiang Shihezi,832002;Shihezi People's Hospital Obstetrics Department,Xinjiang Shihezi,832000;Shihezi Maternal and Child Health Care Hospital Obstetrics Department,Xinjiang Shihezi,832000;People's Hospital of Xinjiang Uygur Autonomous Region Nursing department,Urumqi,830001;People's Hospital of Xinjiang Uygur Autonomous Region Obstetrics Department,Urumqi,830001)

机构地区：[1]石河子大学医学院,新疆石河子832002 [2]石河子市人民医院产科,新疆石河子832000 [3]石河子市妇幼保健院产科,新疆石河子832000 [4]新疆维吾尔自治区人民医院护理部,乌鲁木齐830001 [5]新疆维吾尔自治区人民医院产科,乌鲁木齐830001

出　　处：《农垦医学》2024年第1期56-60,65,共6页Journal of Nongken Medicine

摘　　要：目的:探究妊娠期糖尿病(Gestational Diabetes Mellitus,GDM)孕妇增重状况对焦虑的影响,以及维生素D(Vitamin D,VitD)水平在GDM孕妇增重状况与焦虑之间的中介作用。方法:采用随机整群抽样法选取新疆三所医院产前门诊孕24~28周GDM孕妇299例作为研究对象。孕妇进行葡萄糖耐量试验当日采用标准身高体重仪测量孕妇身高及体重,通过问卷调查收集其一般资料及妊娠相关焦虑情况,采用血清25(OH)D3评估体内VitD水平。并通过产科建档处和电子病历信息系统收集其体重状况。结果:GDM孕妇焦虑的检出率为27.09%。偏相关分析显示,GDM孕妇增重状况与焦虑呈正相关(r=2.981,P<0.001),与VitD水平呈负相关(r=-2.894,P<0.001),VitD水平与焦虑呈正相关(r=-0.164,P<0.001)。中介效应分析结果显示,VitD水平在GDM孕妇增重过多与焦虑之间起到部分中介效应,相对中介效应的效果量为14.48%。结论:GDM孕妇焦虑情况的检出率较高,且VitD水平在GDM孕妇增重过多与焦虑之间起到部分中介效应。Objective:To investigate the influence of weight gain status on anxiety in pregnant women with Gestational Diabetes Mellitus(GDM),and the mediating role of Vitamin D(VitD)level between weight gain status and anxiety in pregnant women with GDM.Methods:On the day of glucose tolerance test,the height and weight of pregnant women were measured by standard height and weight meter.General information and pregnancy-related anxiety were collected by questionnaire survey.Serum 25(OH)D3 was used to assess VitD level in vivo.Their weight status was collected through the obstetrical registry and electronic medical record information syste.Results:The detection rate of anxiety in pregnant women with GDM was 27.09%.Partial correlation analysis showed that weight gain in GDM pregnant women was positively correlated with anxiety(r=2.981,P<0.001),negatively correlated with VitD level(r=-2.894,P<0.001),and VitD level was positively correlated with anxiety(r=-0.164,P<0.001).The results of mediating effect analysis showed that VitD level played a partial mediating effect between excessive weight gain and anxiety in pregnant women with GDM,and the relative mediating effect size was 14.48%.Conclusions:The detection rate of anxiety in GDM pregnant women is high,and VitD level plays a partial mediating effect between weight gain and anxiety in GDM pregnant women.

关 键 词：增重状况 维生素D 焦虑 妊娠期糖尿病 中介效应 

分 类 号：R714.256[医药卫生—妇产科学]