OCTA在神经眼科疾病中应用的研究进展  

Research Progress on the Application of OCTA in Neuro-ophthalmic Diseases

作　　者：刘自强 接传红[1] 王建伟[1] 侯小玉 邓宇 王晶莹 张玮琼 李媛媛 LIU Ziq-iang;JIE Chuanhong;WANG Jianwei;HOU Xiaoyu;DENG Yu;WANG Jingying;ZHANG Weiq-iong;LI Yuanyuan(Eye Hospital,China Academy of Chinese Medical Sciences,Beijing 100040,China)

机构地区：[1]中国中医科学院眼科医院,北京100040

出　　处：《中国中医眼科杂志》2024年第5期477-480,484,共5页China Journal of Chinese Ophthalmology

基　　金：国家自然科学基金项目(81874494);北京市自然科学基金项目(7232325);北京市中医药科技发展资金项目(BJZYYB-2023-57);首都卫生发展科研专项(2020-2-4182,2020-3-4184);中国中医科学院科技创新工程(CI2021A02604)。

摘　　要：光学相干断层扫描血管成像(OCTA)是一种无创的眼底血管成像工具,用来评估视网膜血管,临床上目前多应用于糖尿病视网膜病变、年龄相关性黄斑变性等疾病。OCTA可对视盘、视网膜神经丛甚至脉络膜进行高质量成像,并量化微血管参数,因此可作为沟通神经科学和眼科学的重要手段。本文从神经眼科疾病入手,就OCTA的视盘、黄斑及脉络膜等血管参数在非动脉炎性前部缺血性视神经病变(NAION)、视神经炎(ON)、视盘水肿、神经退行性疾病等疾病中的诊断、鉴别诊断、治疗的应用进行综述,以期为神经眼科疾病的临床诊断治疗提供参考。Optical coherence tomography angiography(OCTA)is a non-invasive retinal vascular imaging tool used to evaluate retinal vasculature.Currently,it is widely applied in clinical settings for eye diseases such as diabetic retinopathy and age-related macular degeneration.OCTA provides high-quality imaging of the optic disc,retinal nerve fiber layer,and even the choroid,allowing for quantitative analysis of microvascular parameters.Therefore,it serves as an important means of communication between neuroscience and ophthalmology.This paper starts from neuroophthalmic diseases and reviews the application of OCTA in diagnosing,differentiating,and treating non-arteritic anterior ischemic optic neuropathy(NAION),optic neuritis(ON),optic disc edema,neurodegenerative diseases,and other diseases based on vascular parameters of the optic disc,macula,and choroid,aiming to provide reference for clinical diagnosis and treatment of neuro-ophthalmic diseases.

关 键 词：神经眼科学 光学相干断层扫描血管成像 应用 

分 类 号：R774[医药卫生—眼科]