乳房外Paget病诊治专家共识(2024版)  

Treatment of extramammary Paget's disease:a Chinese expert consensus statement(2024)

作　　者：《乳房外Paget病诊治专家共识(2024版)》编写委员会专家组 陈翔 商冠宁 陈嵘祎 Writing Committee Expert Group on"Treatment of Extramammary Paget's Disease:a Chinese Expert Consensus Statement(2024)";Chen Xiang;Shang Guanning;Chen Rongyi

机构地区：[1]不详

出　　处：《中华皮肤科杂志》2024年第5期400-408,共9页Chinese Journal of Dermatology

基　　金：国家重点研发计划项目(2022YFC2504700)。

摘　　要：乳房外Paget病是一种少见且易误诊的皮肤恶性肿瘤,其早期病变局限于表皮,也可浸润至真皮层,晚期则可能出现淋巴结转移和远处转移。乳房外Paget病常见于大汗腺分布区域,包括阴囊、阴茎、外阴以及肛周、腹股沟、腋窝等部位,常表现为红色斑片或浸润性斑块,部分皮损伴有鳞屑、糜烂等。在选择治疗方案前,必须对患者进行全面的分期评估。本专家共识基于国际上最新的指南和临床研究成果,结合我国的临床治疗实践,形成了关于乳房外Paget病分期治疗的一线和二线治疗方案以及新型治疗方法,为规范乳房外Paget病的治疗提供依据。Extramammary Paget's disease(EMPD)is a rare and easily misdiagnosed cutaneous malignancy,which is usually confined to the epidermis and can also infiltrate the dermis in the early stage,and presents with lymph node and distant metastases in the advanced stage.EMPD mostly affects the areas rich in apocrine glands,including the scrotum,penis,and vulva,as well as perianal,inguinal and axillary regions.It typically presents as infiltrative erythema or plaques,some of which are accompanied by scales and erosions.Before the treatment,comprehensively assessing the staging of patients is necessary due to the treatment options depending on the tumor stages.Based on the latest international guidelines and clinical research findings,and taking into account the current status of diagnosis and treatment in China,experts reached a consensus on the first-and second-line treatments and novel treatments according to the staging of EMPD,providing a basis for standardizing the treatment of EMPD.

关 键 词：佩吉特病 乳腺外 肿瘤分期 肿瘤治疗方案 专家共识 

分 类 号：R739.5[医药卫生—肿瘤]