多模态成像诊断^(99)Tc^(m)-MIBI显像阴性甲状旁腺癌1例  

Multimodal Imaging in the Diagnosis of^(99)Tc^(m)-MIBI Negative Parathyroid Carcinoma:a Case Report

作　　者：韩云峰 彭丹 HAN Yunfeng;PENG Dan(Department of Nuclear Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Hubei Province Key Laboratory of Molecular Imaging,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属同济医院核医学科,湖北武汉430030 [2]分子影像湖北省重点实验室,湖北武汉430022

出　　处：《标记免疫分析与临床》2024年第4期776-780,共5页Labeled Immunoassays and Clinical Medicine

基　　金：湖北省卫生健康委面上项目(编号:WJ2021M130);分子影像湖北省重点实验室开放基金项目(编号:2023fzyx022)。

摘　　要：甲状旁腺癌(parathyroid carcinoma,PC)是一种罕见的内分泌肿瘤,相比良性原发性甲状旁腺功能亢进症(primary hyperparathyroidism,PHPT),PC常伴有严重的、难治性高钙血症,更容易诱发高钙危象。PC的预后和总生存期取决于原发肿瘤的大小、肿瘤分期、诊断时的侵袭情况以及早期手术切除所有癌组织的可能性,因而准确的术前影像学评估对于PC治疗至关重要。本文报告了多模态成像协助诊断^(99)Tc^(m)-MIBI显像阴性的PC患者1例,辅助了临床诊疗方案制定。此案例说明,多模态影像可以在PC定性、定位、定量、定期上优势互补,有利于PC的术前诊断及预后评价,有助于临床决策。Parathyroid carcinoma(PC)is an extremely rare endocrine tumor.Compared with benign primary hyperparathyroidism(PHPT),PC is usually accompanied with severe and refractory hypercalcemia,and more likely to induce hypercalcemic crisis.The prognosis and overall survival rate of PC depend on the size of the primary tumor,tumor stage,invasion status at the time of the diagnosis,and the possibility of early surgical removal of all cancerous tissue,so accurate preoperative imaging evaluation is essential for PC treatment.This paper reports a case of^(99)Tc^(m)-MIBI negative PC patient diagnosed by multimodal imaging.This case study shows that multimodal imaging can complement each other in PC qualitative,positioning,quantitative and staging,which can be conducive to the preoperative diagnosis and prognosis evaluation of PC,as well as clinical decision-making process.

关 键 词：甲状旁腺癌 ^(99)Tc^(m)-MIBI 多模态成像 

分 类 号：R736.2[医药卫生—肿瘤]