基于慢性疾病轨迹模式的干预对脑胶质瘤术后化疗患者心理弹性、癌因性疲乏及生活质量的影响  

Effects of intervention based on chronic disease trajectory model on the psychological resilience,cancer-related fatigue,and quality of life of postoperative chemotherapy patients with glioma

作　　者：宋冬 丁艮晓[1] 段冉 魏丽莎 SONG Dong;DING Genxiao;DUAN Ran;WEI Lisha(Department of Neurosurgery,He’nan Provincial People’s Hospital/He’nan University People’s Hospital,Zhengzhou 450000,He’nan,China)

机构地区：[1]河南省人民医院/河南大学人民医院神经外科,郑州4500000

出　　处：《癌症进展》2024年第5期507-510,共4页Oncology Progress

基　　金：河南省医学科技攻关计划省部共建重点项目(SBGJ202102009)。

摘　　要：目的探讨基于慢性疾病轨迹模式的干预对脑胶质瘤术后化疗患者心理弹性、癌因性疲乏及生活质量的影响。方法根据干预方式的不同将93例脑胶质瘤术后化疗患者分为对照组(n=46)和观察组(n=47),对照组患者给予常规干预,观察组患者在此基础上给予基于慢性疾病轨迹模式的干预。比较两组患者的心理状态[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、心理弹性[Connor-Davidson心理弹性量表(CD-RISC)]、癌因性疲乏程度[癌症疲乏量表(CFS)]和生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]。结果干预后,两组患者SDS、SAS评分均低于本组干预前,CD-RISC评分均高于本组干预前,观察组患者SDS、SAS评分均低于对照组,CD-RISC评分高于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者行为、感知、认知、情感评分均低于本组干预前,观察组患者行为、感知、认知、情感评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者躯体功能、情绪功能、社会功能、认知功能评分均高于本组干预前,观察组患者躯体功能、情绪功能、社会功能、认知功能评分均高于对照组,差异均有统计学意义(P﹤0.05)。结论基于慢性疾病轨迹模式的干预应用于脑胶质瘤术后化疗患者,可改善患者的心理弹性及不良情绪,减轻癌因性疲乏程度,提高生活质量。Objective To explore the effects of intervention based on chronic disease trajectory model on the psychological resilience,cancer-related fatigue,and quality of life of postoperative chemotherapy patients with glioma.Method A total of 93 postoperative chemotherapy patients with glioma were divided into control group(n=46)and observation group(n=47)according to different treatment methods.The control group received routine intervention,and the observation group received intervention based on chronic disease trajectory model.The psychological status[self-rating anxiety scale(SAS),self-rating depression scale(SDS)],psychological resilience[Connor-Davidson resilience scale(CD-RISC)],cancer-related fatigue degree[cancer fatigue scale(CFS)],and quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)]were compared between the two groups.Result After intervention,the SDS and SAS scores of the two groups were lower than those before intervention,and the CD-RISC scores were higher than those before intervention,the SDS and SAS scores of the observation group were lower than those of the control group,and the CD-RISC score was higher than that of the control group,the differences were statistically significant(P<0.05).After intervention,the behavior,perception,cognition,and emotion scores of the two groups were lower than those before intervention,the behavior,perception,cognition,and emotion scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).After intervention,the scores of physical function,emotional function,social function,and cognitive function in both groups were higher than those before intervention,the scores of physical function,emotional function,social function,and cognitive function in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The intervention based on chronic disease

关 键 词：脑胶质瘤 术后化疗 基于慢性疾病轨迹模式的干预 生活质量 

分 类 号：R739.41[医药卫生—肿瘤]