玻璃体腔注射阿柏西普治疗糖尿病黄斑水肿的临床疗效分析  

Clinical Effect of Intravitreal Injection of Arbocept in the Treatment of Diabetic Macular Edema

作　　者：甄灿灿 杨梅[1] ZHEN Cancan;YANG Mei(Department of Ophthalmology,Jinxiang County People's Hospital,Jining,Shandong Province,272200 China)

机构地区：[1]金乡县人民医院眼科,山东济宁272200

出　　处：《中外医疗》2024年第7期100-104,共5页China & Foreign Medical Treatment

摘　　要：目的探索糖尿病黄斑水肿开展玻璃体腔注射阿柏西普治疗对病症控制情况。方法随机选取2022年1-12月金乡县人民医院收治的70例糖尿病黄斑水肿患者为研究对象,按照随机双色球抽取方式分为对照组和观察组,每组35例。观察组开展玻璃体腔注射阿柏西普治疗,对照组开展玻璃体腔注射曲安奈德治疗,比较两组各项指标治疗情况。结果观察组治疗有效率(94.29%)高于对照组(80.00%),差异有统计学意义(χ^(2)=4.590,P<0.05)。观察组最佳矫正视力、黄斑中心凹陷度、眼压指标优于对照组,差异有统计学意义(P均<0.05)。观察组黄斑总体积、N1波潜伏期、视网膜厚度指标优于对照组,差异有统计学意义(P均<0.05)。观察组生命质量评分高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异无统计学意义(P>0.05)。结论糖尿病黄斑水肿开展玻璃体腔注射阿柏西普治疗疗效显著,安全性较高,可以有效的改善患者视力,降低病症对患者日常生活影响,提高患者生命质量,具有较高的临床应用价值。Objective To explore the control of diabetic macular edema by intravitreal injection of arbocept.Methods Seventy patients with diabetic macular edema treated in Jinxiang County People's Hospital from January to December 2022 were randomly selected as the study objects,and they were divided into control group and observation group ac-cording to random two-color sphere extraction method,with 35 cases in each group.The observation group was treated with intravitreal injection of arbocept,and the control group was treated with intravitreal injection of triamcinolone olone.Results The therapeutic effectieness of observation group(94.29%)was higher than that of control group(80.00%),and the differences were statistically significant(χ^(2)=4.590,P<0.05).The best corrected visual acuity,macu-lar central depression and IOP indexes in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).The indexes of macular total volume,N1 wave latency and retinal thickness in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).The life quality index score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,and the difference was not statistically significant(P>0.05).Conclusion The treat-ment of diabetic macular edema by intravitreal injection of albocep has significant efficacy and high safety,which can effectively improve the vision of patients,reduce the impact of the disease on patients'daily life,and improve the qual-ity of life of patients,and has high clinical application value.

关 键 词：糖尿病黄斑水肿 玻璃体腔注射 阿柏西普 

分 类 号：R774.5[医药卫生—眼科]