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作 者:胡赞 姚永新 Hu Zan;Yao Yongxin(Interventional Department,Xiangtan Central Hospital,Xiangtan 411100,Hunan Province,China)
出 处:《中国社区医师》2024年第9期29-31,共3页Chinese Community Doctors
摘 要:目的:分析血管内微导管介入治疗脑动脉瘤的效果。方法:选取2020年2月—2023年4月湘潭市中心医院收治的脑动脉瘤患者70例作为研究对象。采用随机数字表法分为试验组、参照组,各35例。参照组采用夹闭手术治疗,试验组采用血管内微导管介入治疗。比较两组治疗效果。结果:试验组治疗总有效率高于参照组,差异有统计学意义(P=0.003)。试验组手术时间、住院时间短于参照组,术中出血量少于参照组,差异有统计学意义(P<0.001)。试验组并发症总发生率低于参照组,差异有统计学意义(P=0.046)。治疗后,两组核因子κB、血管内皮生长因子、血清可溶性细胞间黏附分子-1水平低于治疗前,且试验组低于参照组,差异有统计学意义(P<0.05)。结论:血管微导管介入治疗脑动脉瘤的效果较好,可缩短手术时间,减少术中出血量,改善血清指标,降低并发症发生率,促进患者康复。Objective:To analyze the effect of intravascular microcatheter intervention in the treatment of cerebral aneurysm.Methods:A total of 70 patients with cerebral aneurysm admitted to Xiangtan Central Hospital from February 2020 to April 2023 were selected as the study subjects.They were divided into the experimental group and the reference group according to random number table method,with 35 cases in each group.The reference group was treated with clipping surgery,and the experimental group was treated with intravascular microcatheter intervention.The therapeutic effect of the two groups was compared.Results:The overall effective rate of treatment in the experimental group was higher than that in the reference group,and the difference was statistically significant(P=0.003).The operation time and the length of hospital stay in the experimental group were shorter than those in the reference group,and the intraoperative blood loss in the experimental group was less than that in the reference group,with a statistically significant difference(P<0.001).The total incidence of complications in the experimental group was lower than that in the reference group,and the difference was statistically significant(P=0.046).After treatment,the levels of nuclear factor kappa B,vascular endothelial growth factor,and serum soluble intercellular adhesion molecule-1 in the two groups were lower than those before treatment,and the levels in the experimental group were lower than those in the reference group,with a statistically significant difference(P<0.05).Conclusion:Intravascular microcatheter intervention has a good effect in the treatment of cerebral aneurysm,and can shorten the operation time,reduce the amount of intraoperative blood loss,improve serum indexes,reduce the incidence of complications,and promote the recovery of patients.
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