三亚市自然人群幽门螺杆菌感染情况分析  

Analysis of Helicobacter pylori infection in the natural population of Sanya City

作　　者：黄士美 兰连果 张大涯 陈润祥 张晓冬 陈晨 曾凡 李达 黄显凤 汪琦 陈世锔 高蕾 曾俊涛 白飞虎 HUANG Shi-mei;LAN Lian-guo;ZHANG Da-ya;CHEN Run-xiang;ZHANG Xiao-dong;CHEN Chen;ZENG Fan;LI Da;HUANG Xian-feng;WANG Qi;CHEN Shi-ju;GAO Lei;ZENG Jun-tao;BAI Fei-hu(Graduate School of Hainan Medical College,Hainan 571199,China;Department of Gastroenterology,Sanya Central Hospital,Sanya 572000,China;Department of Gastroenterology,Second Affiliated Hospital of Hainan Medical College,Hainan 570216,China;Hainan Digestive Disease Clinical Research Center,Hainan 570216,China)

机构地区：[1]海南医学院研究生院,571199 [2]三亚中心医院消化内科,572000 [3]海南医学院第二附属医院消化内科,570216 [4]海南省消化疾病临床研究中心,570216

出　　处：《现代消化及介入诊疗》2024年第2期141-145,共5页Modern Interventional Diagnosis and Treatment in Gastroenterology

基　　金：海南省临床医学中心建设项目(2021818);海南省院士创新平台科研项目(YSPTZX202313);海南省卫生健康行业科研项目(22A200078);海南省研究生创新科研课题(Qhyb2022-133);海南医学院研究生创新科研课题(HYYB2022A18)。

摘　　要：目的探讨三亚市自然人群幽门螺杆菌(H.pylori)感染现状,分析其影响因素,为防控H.pylori感染提供参考依据。方法采用整体分层随机抽样的方法选取三亚市四个区共677名居民,进行尿素^(14)C呼气试验和问卷调查,计算自然人群H.pylori阳性率,并分析H.pylori感染的影响因素。结果共纳入606名居民,H.pylori阳性检出者为261例,阳性检出率为38.5%。其中不同民族、婚姻状况、吸烟、进食蔬菜瓜果和文化程度与H.pylori感染相关(P<0.05);性别、年龄、BMI、饮酒、饮用水来源、咀嚼槟榔及同住人口数量与H.pylori感染无明显相关(P>0.05)。家人感染是三亚市自然人群H.pylori感染的独立危险因素,黎族、经常食用瓜果蔬菜、大专及以上文化水平是三亚市自然人群H.pylori感染的独立保护因素。结论三亚市自然人群H.pylori感染率低于全国平均水平,多食用瓜果蔬菜、提高卫生防护意识有利于预防H.pylori感染;推广家庭和相关成员同检同治,避免家庭内部聚集性感染。Objective To explore the current status of H.pylori infection in the natural population of Sanya City,analyze its influencing factors,and provide a reference basis for the prevention and control of H.pylori infection.Methods A total of 677 residents from four districts of Sanya City were selected by overall stratified random sampling method,and were subjected to urea 14C breath test and questionnaire survey to calculate the positive rate of H.pylori in the natural population and analyze the influencing factors of H.pylori infection.Results A total of 606 residents were included,and the number of H.pylori positive detections was 261,with a positive detection rate of 38.5%.Among them,different ethnicity,marital status,smoking,eating vegetables and fruits,and literacy level were associated with H.pylori infection(P<0.05);gender,age,BMI,alcohol consumption,drinking water source,betel quid chewing,and the number of cohabitants were not significantly associated with H.pylori infection(P>0.05).Family infection was an independent risk factor for H.pylori infection in the natural population of Sanya City,and Li ethnicity,frequent consumption of fruits and vegetables,and college and higher education level were independent protective factors for H.pylori infection in the natural population of Sanya City.Conclusion The rate of H.pylori infection in the natural population of Sanya City is lower than the national average.Consuming more fruits and vegetables and improving the awareness of hygiene protection are conducive to the prevention of H.pylori infection;and the promotion of the family and related members with the same examination and treatment is important to avoid aggregation of infection within the family.

关 键 词：幽门螺杆菌 ^(14)C尿素呼气试验 感染率 影响因素 三亚市 

分 类 号：R573[医药卫生—消化系统]