原发性肛门瘙痒患者焦虑抑郁情绪、睡眠质量及生活质量分析  

Analysis of anxiety,depression,sleep quality and quality of life in patients with primary pruritus ani

作　　者：陈金兰 熊艺 王聪 王奇[2] 徐利[1] CHEN Jinan;XIONG Yi;WANG Cong;WANG Qi;XU Li(Department of Anorectal Surgery,The First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310006,China;Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310007,China)

机构地区：[1]浙江中医药大学附属第一医院肛肠外科,浙江杭州310006 [2]浙江中医药大学附属杭州市中医院,浙江杭州310007

出　　处：《预防医学》2024年第4期314-316,共3页CHINA PREVENTIVE MEDICINE JOURNAL

基　　金：国家自然科学基金项目(81704082)。

摘　　要：目的了解原发性肛门瘙痒患者大便性状、焦虑抑郁情绪、睡眠质量和生活质量,并分析其与肛门瘙痒症状的相关性,为原发性肛门瘙痒防治提供依据。方法选择浙江中医药大学附属第一医院肛肠科门诊就诊的原发性肛门瘙痒患者,采用视觉模拟评分量表、瘙痒频率评分、医院焦虑抑郁量表、匹兹堡睡眠质量指数量表和简体中文版皮肤病生活质量评分量表进行调查;采用Spearman秩相关分析患者瘙痒程度、频率与焦虑抑郁情绪、睡眠质量、生活质量的相关性。结果纳入原发性肛门瘙痒患者60例,其中男性7例,女性53例;年龄为(34.37±10.30)岁。轻、中、重度瘙痒分别占28.33%、48.33%和23.34%;瘙痒频率1、2、3级分别占51.67%、38.33%和10.00%。焦虑情绪阳性占18.33%;抑郁情绪阳性占13.33%;焦虑和抑郁情绪并存占10.00%。睡眠质量很好、较好、一般和差分别占15.00%、46.66%、30.00%和8.34%。生活质量无、轻度、中度和重度影响分别占10.00%、46.66%、33.34%和10.00%。患者瘙痒程度与焦虑情绪(r_(s)=0.405,P=0.001)、抑郁情绪(r_(s)=0.343,P=0.007)、睡眠质量(r_(s)=0.293,P=0.037)、生活质量(r_(s)=0.338,P=0.008)呈正相关,而瘙痒频率与上述因素未见相关性(均P>0.05)。结论原发性肛门瘙痒患者的瘙痒程度与焦虑抑郁情绪、睡眠质量和生活质量相关。Objective To learn anxiety,depression,sleep quality and quality of life among patients with primary pruri-tus ani,and to analyze their correlation with anal itching symptom,so as to provide insights into the prevention and treatment of primary pruritus ani.Methods Patients with primary pruritus ani were selected from anorectal department of the First Affiliated Hospital of Zhejiang Chinese Medical University.The Visual Analogue Scale,pruritus frequency score,Hospital Anxiety and Depression Scale,Pittsburgh Sleep Quality Index and Dermatology Life Quality Index(Chi-nese version)were used in the survey.Spearman rank correlation analysis was employed to analyze the correlation be-tween the degree and frequency of pruritus ani with,anxiety,depression,sleep quality and quality of life.Results Six-ty patients with primary pruritus ani were investigated,including of 7 males and 53 females,with an average age of(34.37±10.30)years.The patients with mild,moderate and severe pruritus accounted for 28.33%,48.33%and 23.34%,respectively.The patients with pruritus frequency of grade 1,2 and 3 accounted for 51.67%,38.33%and 10.00%,re-spectively.The patients with anxiety,depression,and coexistence of anxiety and depression accounted for 18.33%,13.33%and 10.00%,respectively.The patients with very good,good,average and poor sleep quality accounted for 15.00%,46.66%,30.00%and 8.34%,respectively.No,mild,moderate and severe impacts on quality of life among the patients accounted for 10.00%,46.66%,33.34%and 10.00%,respectively.The degree of pruritus was positively correlat-ed with anxiety(r_(s)=0.405,P=0.001),depression(r_(s)=0.343,P=0.007),sleep quality(r_(s)=0.293,P=0.037)and quality of life(r_(s)=0.338,P=0.008).However,there was no significant correlation between the frequency of pruritus with the above fac-tors(all P>0.05).Conclusion The degree of pruritus in patients with primary pruritus ani is related to anxiety,depres-sion,sleep quality and quality of life.

关 键 词：原发性肛门瘙痒 焦虑 抑郁 生活质量 睡眠质量 

分 类 号：R574.8[医药卫生—消化系统]