T_(2)mapping技术在鉴别直肠黏液腺癌和非黏液腺癌中的价值  

Value of T_(2)mapping technique in distinguishing rectal mucinous adenocarcinoma and non-mucinous adenocarcinoma

作　　者：吴广太 贾进正 徐兴华[1] 常玲玉 程连华 王林红[1] 王青[1] 王芳[1] WU Guangtai;JIA Jinzheng;XU Xinghua;CHANG Lingyu;CHENG Lianhua;WANG Linhong;WANG Qing;WANG Fang(Department of Radiology,Qilu Hospital of Shandong University,Jinan 250012,China;Department of Radiology,Pingdu Hospital of Traditional Chinese Medicine,Qingdao 266700,China;Cheeloo College of Medicine,Shandong University,Jinan 250012,China)

机构地区：[1]山东大学齐鲁医院放射科,山东济南250012 [2]山东省平度市中医医院放射科,山东青岛266700 [3]山东大学齐鲁医学院,山东济南250012

出　　处：《中国中西医结合影像学杂志》2024年第3期333-337,共5页Chinese Imaging Journal of Integrated Traditional and Western Medicine

基　　金：山东省自然科学基金项目(ZR2019MH049)。

摘　　要：目的:探讨T_(2)mapping技术对直肠黏液腺癌和非黏液腺癌的鉴别诊断价值。方法:前瞻性纳入直肠癌患者69例,其中黏液腺癌9例,非黏液腺癌60例,所有患者均行盆腔MRI检查,扫描序列包括T_(2)mapping及DWI序列。由2位经验丰富的放射科医师独立测量病灶的T_(2)值及ADC值,采用独立样本t检验或Mann-Whitney U检验比较不同病理类型肿瘤各参数值的差异。采用ROC曲线和DeLong检验分析T_(2)值、ADC值及两者联合的诊断效能。结果:直肠黏液腺癌的T_(2)值及ADC值均高于非黏液腺癌,差异均有统计学意义(均P<0.05)。T_(2)值、ADC值及联合指标(T_(2)值+ADC值)鉴别直肠黏液腺癌和非黏液腺癌的AUC分别为0.96、0.81和0.97,T_(2)值与ADC值的差异及联合指标与ADC值的差异均有统计学意义(均P<0.05)。结论:T_(2)mapping对直肠黏液腺癌与非黏液腺癌的鉴别诊断效能优于DWI,DWI联合T_(2)mapping可显著提高对直肠黏液腺癌与非黏液腺癌的鉴别诊断准确率。Objective:To investigate the value of T_(2)mapping in distinguishing rectal mucinous adenocarcinoma and non-mucinous adenocarcinoma.Methods:Sixty-nine patients with rectal cancer(9 patients with mucinous adenocarcinoma,60 patients with non-mucinous adenocarcinoma)underwent pelvic MRI T_(2)mapping and DWI.T_(2)and ADC values of lesions were measured independently by two experienced radiologists,and the differences between mucinous and non-mucinous adenocarcinoma were compared using independent sample t test or Mann-Whitney U test.The ROC curve and DeLong test were used to test the diagnostic efficiency of T_(2)and ADC values.Results:T_(2)and ADC values of rectal mucinous adenocarcinoma were higher than those of non-mucous adenocarcinoma(both P<0.05).AUCs of T_(2)value,ADC value and the combined indicators(T_(2)+ADC)in distinguishing rectal mucinous adenocarcinoma and non-mucinous adenocarcinoma were 0.96,0.81 and 0.97,respectively,and the AUC of T_(2)value and the combined indicators were statistically different with that of ADC value(both P<0.05).Conclusions:T_(2)mapping has a higher diagnostic efficiency in differentiating rectal mucinous and non-mucinous adenocarcinoma than DWI.And DWI combined with T_(2)mapping can significantly improve the diagnostic accuracy.

关 键 词：直肠肿瘤 磁共振成像 T_(2)mapping 扩散加权成像 黏液腺癌 

分 类 号：R735.37[医药卫生—肿瘤]