改良电休克联合抗精神病药物治疗女性难治性精神分裂症的疗效对比观察  

Curative Effect Comparison of Modified Electroconvulsive Therapy Combined with Antipsychotic Drugs in Treatment of Female Refractory Schizophrenia

作　　者：王晓星 李秋林 WANG Xiaoxing;LI Qiulin(Chibi City Pufang Hospital,Chibi,Hubei,437300)

机构地区：[1]赤壁市蒲纺医院,湖北赤壁437300

出　　处：《智慧健康》2024年第4期57-60,共4页Smart Healthcare

摘　　要：目的 观察改良电休克配合抗精神病药物治疗女性难治性精神分裂症的临床效果。方法 随机抽取2022年1月—2023年6月本院收治的难治性精神分裂症女性患者82例作为研究对象,依据病例尾号奇偶数将患者分为对照组和观察组,每组41例。对照组患者单纯使用抗精神病药物治疗,观察组患者实施改良电休克联合抗精神病药物治疗。对比两组患者治疗的临床疗效及治疗前后的操作智商、语言智商、焦虑程度、抑郁程度。结果 与对照组相比,观察组患者的治疗总有效率更高(P<0.05);治疗后,两组患者的操作智商和语言智商评分较治疗前均有所提高,但观察组操作智商和语言智商评分高于对照组(P<0.05);治疗后,两组患者的SDS和SAS评分较治疗前均有所降低,观察组的SDS和SAS评分降低幅度低于对照组(P<0.05)。结论 难治性精神分裂症的女性患者使用改良电休克联合抗精神病药物治疗可以获得较好的治疗效果,同时可以有效提高患者的认知能力,缓解负面情绪,具有很高的医学价值。Objective To observe clinical effect of modified electroconvulsive therapy combined with antipsychotic drugs in treatment of female refractory schizophrenia.Methods The paper chose 82 female patients with refractory schizophrenia admitted to our hospital from January 2022 to June 2023 as study subjects,and divided them into control group and observation group randomly according to odd even principle of case tail numbers,with 41 cases in each group.Control group was treated with antipsychotic drugs only,while observation group with modified electroconvulsive therapy combined with antipsychotic drugs.Clinical Effect,operational intelligence,language intelligence,anxiety level,and depression level was compared before and after treatment between two groups.Results Total effective rate of treatment in observation group was higher than control group(P<0.05).After treatment,scores of operational intelligence and language intelligence in both groups were higher than before treatment,improvement of operational intelligence and language intelligence scores in observation group were higher than control group(P<0.05).After treatment,anxiety and depression scores of both groups were lower than before treatment.Observation group had lower decrease in anxiety and depression scores than control group(P<0.05).Conclusion Modified electroconvulsive therapy combined with antipsychotic drugs can achieve good curative effect,effectively improve cognitive abilities,alleviate negative emotions of female patients with refractory schizophrenia,which has high medical value.

关 键 词：改良电休克 难治性精神分裂症 抗精神病药物 女性 疗效 

分 类 号：R749.3[医药卫生—神经病学与精神病学]