益生菌结合罂粟碱治疗缺血性肠病的临床疗效研究  

Clinical Efficacy of Probiotics Combined with Papaverine in the Treatment of Ischemic Bowel Disease

作　　者：张慧 Zhang Hui(Renhuai People’s Hospital,Renhuai,Guizhou 564500)

机构地区：[1]仁怀市人民医院,贵州遵义564500

出　　处：《科技与健康》2024年第7期41-44,共4页Technology and Health

摘　　要：分析在缺血性肠病患者的临床治疗中实施益生菌联合罂粟碱治疗的效果。选取2021年1月—2022年12月仁怀市人民医院收治的80例缺血性肠病患者为研究对象,采用随机抽样法将患者分为参照组和实验组,每组各40例,在基础治疗上,给予参照组患者罂粟碱治疗,实验组在参照组基础上联合益生菌治疗,比较两组患者的症状改善情况、治疗前后D-二聚体、血液流变学指标、治疗效果和不良反应发生率。结果显示,实验组患者的肠道血供恢复时间、肠功能恢复时间、腹痛缓解时间、腹泻缓解时间、便血缓解时间相较于参照组更短(P<0.05);治疗后,实验组患者的D-二聚体水平、血液流变学指标优于参照组(P<0.05);实验组患者的治疗总有效率高于参照组(P<0.05);两组患者不良反应发生率比较,差异不具有统计学意义(P>0.05)。研究发现,在缺血性肠病患者的临床治疗中实施益生菌结合罂粟碱治疗的效果显著,可促进患者康复,改善患者的临床症状,安全性较高,值得推广。Analyze the effectiveness of probiotic combined with papaverine in the clinical treatment of patients with ischemic bowel disease.80 patients with ischemic bowel disease admitted to Renhuai People’s Hospital from January 2021 to December 2022 were selected as the research subjects.The patients were randomly divided into a reference group and an experimental group,with 40 cases in each group.In addition to basic treatment,the reference group was treated with papaverine,while the experimental group was treated with probiotics in combination with the reference group.The symptom improvement,D-dimer levels before and after treatment,hemorheological indicators,treatment efficacy,and incidence of adverse reactions were compared between the two groups.The results showed that the recovery time of intestinal blood supply,intestinal function,abdominal pain,diarrhea,and rectal bleeding in the experimental group were shorter than those in the control group(P<0.05);After treatment,the D-dimer level and hemorheological indicators of the experimental group were better than those of the control group(P<0.05);The total effective rate of treatment in the experimental group was higher than that in the control group(P<0.05);There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients(P>0.05).Research has found that the combination of probiotics and papaverine has a significant effect on the clinical treatment of patients with ischemic bowel disease.It can promote patient recovery,improve clinical symptoms,and has high safety,which is worth promoting.

关 键 词：益生菌 罂粟碱 缺血性肠病 治疗效果 

分 类 号：R574[医药卫生—消化系统]