改良小切口手术与传统甲状腺切除术治疗甲状腺瘤的临床效果比较  

Comparison of clinical effects between modified small incision surgery and traditional thyroidectomy in the treatment of thyroid tumors

作　　者：顾建龙[1] GU Jian-long(Yancheng Sheyang County Hospital of Traditional Chinese Medicine,Yancheng 224300,China)

机构地区：[1]盐城市射阳县中医院,224300

出　　处：《中国实用医药》2024年第8期70-73,共4页China Practical Medicine

摘　　要：目的 探究改良小切口手术治疗甲状腺瘤的临床疗效。方法 60例甲状腺瘤患者,将入院序列数作为分组基础,应用随机分组原则分为对照组和观察组,每组30例。对照组采用传统甲状腺切除术,观察组采用改良小切口手术。比较两组手术相关指标、疼痛程度、并发症发生率及手术前后甲状腺功能指标[游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)]、应激指标[皮质醇(Cor)、去甲肾上腺素(NE)]。结果 观察组手术时间(54.32±9.71)min、住院时间(4.35±0.74)d短于对照组的(62.03±10.02)min、(7.12±0.66)d,术中出血量(53.00±5.96)ml少于对照组的(85.97±6.80)ml,切口大小(4.53±0.46)cm小于对照组的(7.11±0.62)cm(P<0.05)。观察组视觉模拟评分法(VAS)评分为(2.38±0.19)分,低于对照组的(5.09±0.48)分(t=28.753, P=0.000<0.05)。观察组并发症发生率3.33%低于对照组的20.00%(P<0.05)。术后,观察组FT3(5.84±0.96)pmol/L、FT4(5.32±1.01)pmol/L高于对照组的(5.32±1.01)、(12.99±2.49)pmol/L, TSH(2.08±0.59)mU/L低于对照组的(2.57±0.76)mU/L(P<0.05)。观察组术后Cor水平为(251.62±13.31)μg/L,低于对照组的(283.06±10.61)μg/L(P<0.05)。观察组术后NE水平为(333.10±12.42)ng/L,低于对照组的(406.08±12.61)ng/L(P<0.05)。结论 对甲状腺瘤患者采用改良小切口手术治疗,能够取得优良的治疗效果,同时可以改善手术过程中的指标、患者的疼痛情况、并发症发生情况以及应激情况,值得推广与应用。Objective To explore the clinical efficacy of modified small incision surgery and traditional thyroidectomy in the treatment of thyroid tumors.Methods 60 patients with thyroid tumor were invited to participate in the study.The sequence number of patients admitted to the hospital was used as the basis for grouping,and the patients were divided into a control group and an observation group,each with 30 cases.The control group was given traditional thyroidectomy,and the observation group was given modified small incision surgery.Both groups were compared in terms of operation-related indicators,degree of pain,incidence of complications,thyroid function indicators[free triiodothyronine(FT3),free thyroxine(FT4),thyroid stimulating hormone(TSH)],stress indicators[cortisol(Cor),norepinephrine(NE)]before and after surgery.Results The operation time and hospitalization time in the observation group were(54.32±9.71)min and(4.35±0.74)d,which were shorter than(62.03±10.02)min and(7.12±0.66)d in the control group;the observation group had less intraoperative blood loss of(53.00±5.96)ml than(85.97±6.80)ml in the control group;the observation group had smaller incision size of(4.53±0.46)cm than(7.11±0.62)cm in the control group(P<0.05).The observation group had lower visual analogue scale(VAS)score of(2.38±0.19)points,which was lower than(5.09±0.48)points in the control group(t=28.753,P=0.000<0.05).The complication rate of the observation group was 3.33%,which was lower than 20.00%of the control group(P<0.05).After surgery,the observation group had FT3 of(5.84±0.96)pmol/L and FT4 of(5.32±1.01)pmol/L,which were higher than(5.32±1.01)and(12.99±2.49)pmol/L in the control group;the observation group had lower TSH of(2.08±0.59)mU/L than(2.57±0.76)mU/L in the control group(P<0.05).After surgery,the observation group had Cor level of(251.62±13.31)μg/L,which was lower than(283.06±10.61)μg/L in the control group(P<0.05).After surgery,the NE level of the observation group was(333.10±12.42)μg/L,which was lower than(4

关 键 词：改良小切口手术 甲状腺瘤 手术相关指标 疼痛程度 并发症发生率 甲状腺功能 应激水平 

分 类 号：R736.1[医药卫生—肿瘤]