嗜铬细胞瘤合并副神经节瘤的研究进展  

Research advances in pheochromocytoma combined with paraganglioma

作　　者：许义贞 张争[2] 高莹[1] 张俊清[1] Xu Yizhen;Zhang Zheng;Gao Ying;Zhang Junqing(Department of Endocrinology,Peking University First Hospital,Beijing 100034,China;Department of Urology,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院内分泌科,北京100034 [2]北京大学第一医院泌尿外科,北京100034

出　　处：《国际内分泌代谢杂志》2024年第2期93-97,共5页International Journal of Endocrinology and Metabolism

摘　　要：嗜铬细胞瘤(pheochromocytoma, PCC)和副神经节瘤(paraganglioma, PGL)是罕见的神经内分泌肿瘤, 两者可单独发生, 也可同时发生, 但PCC合并PGL者更为罕见。因该病具有PCC和PGL的临床特点, 病情复杂, 且PCC合并PGL可在不同时期发生, 故容易漏诊。因此, 提高对PCC合并PGL的认识, 对PPGL患者的诊治和随访有重要意义。本文通过对PCC合并PGL的流行病学、遗传学、临床表现、诊断方法、治疗及预后等研究进展作一综述, 以提高临床医师对于该病的认识。Pheochromocytoma(PCC)and paraganglioma(PGL)are rare neuroendocrine tumors,that can occur separately or simultaneously.However,the PCC combined with PGL is even rarer.Since the PCC combined with PGL has the clinical characteristics of both PCC and PGL,together with the complex conditions,and it can be nonsynchronous,it is easy to be misdiagnosed.Therefore,improving the understanding of PCC combined with PGL is of great significance for the diagnosis,treatment,and follow-up of PPGL patients.This article will review the progress in the epidemiology,genetics,clinical manifestations,diagnostic methods,treatment,and prognosis of PCC combined with PGL,in order to improve the clinicians′understanding of this disease.

关 键 词：嗜铬细胞瘤 副神经节瘤 嗜铬细胞瘤合并副神经节瘤 

分 类 号：R739.4[医药卫生—肿瘤]