CCHFV entry via LDLR keeps it‘ticking’?  

作　　者：Ahmed K.Oraby David J.Marchant 

机构地区：[1]Department of Medical Microbiology and Immunology,University of Alberta,Edmonton,AB T6G 2R3,Canada

出　　处：《Cell Research》2024年第4期271-272,共2页细胞研究（英文版）

摘　　要：Endemic in Africa,the Balkans,the Middle East,and Asia,Crimean-Congo hemorrhagic fever virus(CCHFV)is transmitted from a tick vector to humans and the mortality rates can be as high as 40%.In a recent paper in Cell Research,Xu et al.reports the discovery of LDLR as the CCHFV entry receptor in humans and mice,which may provide clues to the receptor that the virus uses in its tick vector,a major discovery that opens up new and much needed options for therapeutic development.

关 键 词：LDLR CCHF FEVER 

分 类 号：R373[医药卫生—病原生物学]