重复经颅磁刺激治疗创伤后抑郁症的临床研究进展  

Recent advance in clinical application of transcranial magnetic stimulation in post-traumatic depression

作　　者：李琪 张红[1] 杨文东 李贺[1] 徐萌萌 李贞兰[1] Li Qi;Zhang Hong;Yang Wendong;Li He;Xu Mengmeng;Li Zhenlan(Department of Rehabilitation Medicine,First Hospital of Jilin University,Changchun 130000,China)

机构地区：[1]吉林大学第一医院康复医学科,长春130000

出　　处：《中华神经医学杂志》2024年第3期304-309,共6页Chinese Journal of Neuromedicine

摘　　要：创伤后抑郁症(PTD)是创伤性脑损伤(TBI)后出现的严重并发症之一,发病率较高,影响患者的康复治疗、转归和生活质量。由于PTD的发病机制尚不明确,目前临床尚未找到有效的治疗手段。重复经颅磁刺激(rTMS)作为一种新的非侵入性神经调控技术,已经被用于重度抑郁症的治疗。目前rTMS用于PTD治疗的临床证据不足,尚未明确最佳的rTMS治疗方案。本文围绕近年来rTMS治疗PTD的临床研究进展进行综述,以期为其临床应用提供借鉴。Post traumatic depression(PTD)is a serious complication after traumatic brain injury,with high incidence rate;PTD seriously affects the rehabilitation,outcome and quality of life of patients.Due to unclear pathogenesis of PTD,effective treatments have not yet been found in clinical practice.Repetitive transcranial magnetic stimulation(rTMS),as a new non-invasive neuroregulatory technique,has been used in major depression disorder(MDD).Few clinical evidence on PTD treated by rTMS is noted and optimal rTMS treatment regimen has not yet been defined.This article reviews the clinical studies of rTMS in PTD in recent years,with a view to provide references for clinical application.

关 键 词：创伤后抑郁症 创伤性脑损伤 重复经颅磁刺激 

分 类 号：R749.4[医药卫生—神经病学与精神病学]