叶黄素的护眼机制及其在近视防治中的应用进展  

Progress of lutein in the eye protection mechanism and its application in myopia prevention and treatment

作　　者：苏娟 杨永安 沈智蓉 郭杨军 孙宏顺 SU Juan;YANG Yong’an;SHEN Zhirong;GUO Yangjun;SUN Hongshun(Nanjing Polytechnic Institute,Jiangsu Engineering Research Center of Molecular Imaging Probe,Jiangsu Province,Nanjing 210048,China;Jiangsu Nanda Nature Biotechnology Co.Ltd.,Jiangsu Province,Lianyungang 222006,China;Nanjing Jiutian Biomedical Technology Co.Ltd.,Jiangsu Province,Nanjing 210031,China)

机构地区：[1]南京科技职业学院江苏省分子影像探针工程研究中心,江苏南京210048 [2]江苏南大耐雀生物技术有限公司,江苏连云港222006 [3]南京九天生物医疗科技有限公司,江苏南京210031

出　　处：《妇儿健康导刊》2024年第9期17-20,67,共5页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

基　　金：江苏省自然科学基金面上项目(BK20181486);江苏高校“青蓝工程”培养计划(苏教师[2019]3号);南京科技职业学院科研北斗计划项目(NJPI-2022-02,NJPI-RC-2023-02)。

摘　　要：随着电子产品的普及,我国儿童青少年近视呈高发、低龄、重度趋势,亟须采取有效的措施提升视力健康水平。叶黄素作为视网膜黄斑区富含的营养色素,具有蓝光过滤、抗氧化、抗炎等功效,在改善近视及其预后方面有积极作用。本文从叶黄素的性质及来源、生物安全性、护眼机制以及在防治近视中的作用进行综述,并对未来叶黄素的临床研究方向进行展望。With the popularity of electronic products,myopia among children and adolescents in China has become more and more severe in younger age.It is urgent to take effective measures to improve the level of vision health.Lutein,as a nutritional pigment rich in the macular area of the retina,has the functions of blue light filtering,anti-oxidation and antiinflammation,and has a positive effect on improving myopia and its prognosis.This article reviews the properties and sources of lutein,biological safety,eye protection mechanism,and its role in the prevention and treatment of myopia,and looks forward to the future clinical research direction of lutein.

关 键 词：叶黄素 护眼功能 近视 生物安全性 

分 类 号：R944[医药卫生—药剂学]