疏血通注射液治疗缺血性脑卒中的效果评价  

Effect evaluation of Shuxuetong Injection in the treatment of ischemic stroke

作　　者：邓永雄 毕海权 DENG Yongxiong;BI Haiquan(Department of Internal Medicine,Yongchuan Huimin Traditional Chinese Medicine Hospital,Chongqing 402171,China;General Ward,the First Affliated Hospital of Chongqing Medical and Pharmaceutical College,Chongqing 402160,China)

机构地区：[1]重庆市永川惠民中医医院内科,重庆402171 [2]重庆医药高等专科学校附属第一医院综合病区,重庆402160

出　　处：《中国当代医药》2024年第13期15-18,23,共5页China Modern Medicine

摘　　要：目的探讨疏血通注射液治疗缺血性脑卒中的效果。方法选取2019年1月至2023年5月重庆市永川惠民中医医院收治的49例缺血性脑卒中患者作为研究对象,按照随机数字表法将其分为对照组(24例)与观察组(25例),对照组采用阿司匹林与氯吡格雷治疗,观察组在对照组治疗方法的基础上加用疏血通注射液治疗。比较两组患者的临床疗效及治疗期间出血发生情况,并比较两组治疗前后的凝血功能及疾病相关评分。结果观察组治疗后的总有效率高于对照组,出血总发生率低于对照组,差异有统计学意义(P<0.05)。两组患者治疗后的活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)均长于本组治疗前,国际标准化比值(INR)、Barthel指数(BI)评分均高于本组治疗前,D-二聚体(D-D)水平、美国国立卫生院卒中量表(NIHSS)评分、中医症状积分均低于本组治疗前,差异有统计学意义(P<0.05)。观察组患者治疗后的APTT、PT均长于对照组,INR值高于对照组,D-D水平、NIHSS评分、中医症状积分均低于对照组,差异有统计学意义(P<0.05)。结论疏血通注射液治疗缺血性脑卒中能有效提升临床疗效,对患者凝血功能和神经功能进行改善,降低出血发生率,并提升患者日常生活能力。Objective To explore the effect of Shuxuetong Injection in the treatment of ischemic stroke.Methods From January 2019 to May 2023,a total of 49 patients with ischemic stroke in Yongchuan Huimin Traditional Chinese Medicine Hospital of Chongqing City were selected as the research objects,and they were divided into control group(24 cases)and observation group(25 cases)according to random number table method.The control group were treated with Aspirin and Clopidogrel,while the observation group were treated with Shuxuetong Injection on the basis of the treatment of the control group.The clinical efficacy and the incidence of bleeding during treatment were compared between the two groups,and the coagulation function and disease-related scores before and after treatment were compared between the two groups.Results After treatment,the total effective rate of the observation group was higher than that of the control group,and the total incidence of bleeding was lower than that of the control group,and the differences were statistically significant(P<0.05).After treatment,the activated partial thromboplastin time(APTT)and prothrombin time(PT)of the two groups were longer than those before treatment,the international normalized ratio(INR)and Barthel index(BI)score of the two groups were higher than those before treatment,the D-dimer(D-D)level,the national institutes of health stroke scale(NIHSS)score and the traditional Chinese medicine symptom score of the two groups were lower than those before treatment,and the differences were statistically significant(P<0.05).After treatment,the APTT and PT of the observation group were longer than those of the control group,the INR value and BI score of the observation group were higher than those of the control group,and the D-D level,the NIHSS score and the traditional Chinese medicine symptom score of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion Shuxuetong Injection can effectively improve t

关 键 词：缺血性脑卒中 疏血通注射液 凝血功能 出血转化 

分 类 号：R743.3[医药卫生—神经病学与精神病学]